Inventors:
Ivor J. Benjamin - Salt Lake City UT, US
Namakkal S. Rajasekaran - Salt Lake City UT, US
Thomas P. Kennedy - Charlotte NC, US
Assignee:
UNIVERSITY OF UTAH RESEARCH FOUNDTION - SALT LAKE CITY
International Classification:
A01K 67/027, A61K 31/16, A61K 31/27, A61P 9/10, A61K 38/38, A61K 31/566, A61P 3/10, C12N 15/09, A61K 38/02
US Classification:
800 9, 800 21, 514599, 514507, 514 11, 514 69, 514 164, 514 152, 514178, 514177
Abstract:
Disclosed herein is a non-human animal model of protein aggregation cardiomyopathy. Also disclosed are compo-sitions and methods of treating or preventing a condition in a subject caused or exacerbated by reductive stress. Also disclosed are compositions and methods of predicting, detecting, or monitoring reductive stress in a subject.