Inventors:
Irving H. Leopold - Newport Beach CA
Assignee:
Allergan Pharmaceuticals, Inc. - Irvine CA
International Classification:
A61K 31165
Abstract:
An ophthalmic composition comprising a compound having the structural formula ##STR1## wherein X is selected from the group consisting of CH. sub. 2 --CH. sub. 2, CH. sub. 2 and OCH. sub. 2 ; and Y is selected from the group consisting of phenyl, P-methoxy phenyl and O-methoxy phenyl and a pharmaceutically acceptable salt thereof and a topically administrable ophthalmic pharmaceutical carrier. The foregoing composition is useful in lowering intraocular pressure in the eye. Reduction of intraocular pressure is of particular importance in the treatment of glaucoma, a disease characterized by elevated intraocular pressure.