Inventors:
J. Adam Willardsen - Draper UT, US
Jeffrey W. Lockman - Princeton Junction NJ, US
Brett R. Murphy - Collbran CO, US
Weston R. Judd - Farmington UT, US
In Chul Kim - Louisville KY, US
Se-Ho Kim - Salt Lake City UT, US
Daniel Feodore Zigar - Salt Lake City UT, US
Kraig M. Yager - Murray UT, US
Tracey C. Fleischer - Sandy UT, US
Ryan T. Terry-Lorenzo - Marlborough MA, US
J. Jay Boniface - Salt Lake City UT, US
Daniel P. Parker - Sandy UT, US
Ian A. McAlexander - Salt Lake City UT, US
Matthew Gregory Bursavich - Needham MA, US
David M. Dastrup - Columbus OH, US
Assignee:
Myrexis, Inc. - Salt Lake City UT
International Classification:
A61K 31/549, C12N 5/02, A61K 31/5377, A61K 31/50, A61K 31/519, A61K 31/47, A61K 31/4545, A61K 31/4406, A61K 31/4402, A61K 31/357, A61K 31/17, C07D 417/12, C07D 413/12, C07D 237/20, C07D 471/04, C07D 215/46, C07D 401/12, C07D 211/98, C07D 211/04, C07D 317/46, C07C 275/40, A61P 35/00, A61P 29/00, A61P 19/02, A61P 3/04, A61P 3/10, A61P 9/10, C12Q 1/02
US Classification:
5142232, 435 29, 435375, 5142355, 514247, 5142641, 514313, 514318, 514352, 514357, 514466, 514597, 544 13, 544131, 544224, 544279, 546162, 546194, 546312, 546330, 546331, 549441, 564 49
Abstract:
The invention relates to compounds, pharmaceutical compositions and methods useful for treating cancer, systemic or chronic inflammation, rheumatoid arthritis, diabetes, obesity, T-cell mediated autoimmune disease, ischemia, and other complications associated with these diseases and disorders.