ILO ELMAR LEPPIK, M.D.
Neurology at Wayzata Blvd, Minneapolis, MN

2007018, Aug 9, 2007

Oct 2, 2006

11/542520

James Cloyd - Edina MN, US
Angela Birnbaum - Minneapolis MN, US
Ilo Leppik - Minneapolis MN, US
Stephen Collins - Lake Forest IL, US

A61K 31/724, C08B 30/18, C08B 37/16

514058000, 514217000, 536046000

The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2-hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Pat. Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5% dextrose in water), physiological saline, and similar fluids suitable for parenteral administration.

2010020, Aug 12, 2010

Sep 30, 2009

12/571039

James Cloyd - Edina MN, US
Angela Birnbaum - Minneapolis MN, US
Ilo Leppik - Minneapolis MN, US
Stephen D. Collins - Lake Forest IL, US

A61K 31/724, C08B 37/16, A61P 25/08

514 58, 5361231, 536124

The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2-hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Pat. Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5% dextrose in water), physiological saline, and similar fluids suitable for parenteral administration.

2013007, Mar 21, 2013

Nov 16, 2012

13/679715

H. Lundbeck LLC - Deerfield IL, US
Angela BIRNBAUM - Minneapolis MN, US
Ilo LEPPIK - Minneapolis MN, US
Stephen D. COLLINS - Lake Forest IL, US

H. LUNDBECK LLC - Deerfield IL

A61K 31/55, A61K 47/40

514217

The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2-hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Pat. Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5% dextrose in water), physiological saline, and similar fluids suitable for parenteral administration.

2014008, Mar 20, 2014

Oct 11, 2013

14/051938

Angela BIRNBAUM - Minneapolis MN, US
Ilo LEPPIK - Minneapolis MN, US
Stephen D. COLLINS - Lake Forest IL, US

LUNDBECK LLC - Deerfield IL

A61K 47/40, A61K 9/00, A61K 31/55

514217

The present invention is directed to a carbamazepine-cyclodextrin inclusion complex useful for the parenteral administration of carbamazepine. The carbamazepine-cyclodextrin inclusion complex is prepared by the admixture of a modified cyclodextrin and carbamazepine in a physiologically acceptable fluid. Modified cyclodextrins include 2-hydroxypropyl-beta-cyclodextrin and sulfoalkyl cyclodextrins. More particularly, the sulfoalkyl cyclodextrins are those described and disclosed in U.S. Pat. Nos. 5,134,127 and 5,376,645. A physiologically acceptable fluid includes sterile isotonic water, Ringer's lactate, D5W (5% dextrose in water), physiological saline, and similar fluids suitable for parenteral administration.