Inventors:
Alastair William Wark - Irvine CA, US
Hye Jin Lee - Irvine CA, US
Robert Marcus Corn - Corona del Mar CA, US
Voula Kodoyianni - Madison WI, US
Assignee:
Wisconsin Alumni Research Foundation - Madison WI
International Classification:
C12M 1/34
US Classification:
4352872, 385 12, 385129, 385130, 422 8205, 422 8211, 435 6, 4352879, 4352887, 435808, 435973, 436164, 436524, 436525, 436805, 436809
Abstract:
A substrate for testing a carrier liquid for biomolecules using SPR or other techniques provides a metallic island surrounded by a hydrophobic layer, the islands being a location for the attachment of probe molecules. The hydrophobic layer may also be a dielectric material providing improved sensitivity in SPR imaging.