Inventors:
Matthew Cooper - Palo Alto CA, US
Deborah Kinch - Boston MA, US
Michael Rosenberg - Issaquah WA, US
S. Subramaniam - Sharon MA, US
Suzanne Szak - Arlington MA, US
Huo Li - Winchester MA, US
Raj Bandaru - Malden MA, US
Maher Derbel - Arlington MA, US
Assignee:
Biogen Idec MA Inc. - Cambridge MA
International Classification:
C12Q 1/70, C12Q 1/68, C12M 3/00
US Classification:
435005000, 435006000, 435287200
Abstract:
This invention relates to a nucleotide array containing polynucleotide probes complementary to, or fragments of, Cynomolgus monkey genes, and the use of such a nucleotide array to characterize the biological effects, including the actions, targets, and toxicities, of therapeutic agents in primates, e.g., a human, a Cynomolgus monkey, or a Rhesus monkey, in particular a nucleotide array to be used in identifying the toxicities of therapeutic agents administered to a non-human primate, e.g., a Cynomolgus monkey or a Rhesus monkey.