HOWARD SEEHERMAN
Veterinary in Cambridge, MA
License number
Massachusetts 2582
Issued Date
Jun 14, 1982
Expiration Date
Feb 28, 2013
Type
Veterinarian
Address
Address
Cambridge, MA 02140
Personal information
See more information about HOWARD SEEHERMAN at radaris.comName
Address
Phone
327 Lowell Ave, Newtonville, MA 02460
46 Trowbridge St #B, Cambridge, MA 02138
46 Trowbridge St, Cambridge, MA 02138
307 Cabot St, Newtonville, MA 02460
307 Cabot St, Newtonville, MA 02460
Professional information
Vice President
Position:
Vice President-BMP Program Development at Bioventus, Founder at Restituo LLC
Location:
Greater Boston Area
Industry:
Pharmaceuticals
Work:
Bioventus
- Boston MA since Jul 2013
-
Vice President-BMP Program Development
Restituo LLC
- Cambridge, MA since Jan 2012
-
Founder
Pfizer
- Cambridge, MA Jan 2011 - Mar 2012
-
Vice President, Inflamation and Remodeling
Pfizer
- Cambridge, Ma Oct 2009 - Jan 2011
-
Vice President/CSO, Tissue Repair Research Unit
Wyeth Research
Jan 2009 - Oct 2009
-
Vice President, Musculoskeletal Therapies
Wyeth Research
Jan 2007 - Jan 2009
-
Distinguished Wyeth Research Fellow
Wyeth Research
Dec 1996 - Jan 2007
-
Senior Scientist, Associate Director, Director
Genetics Institute
- Cambridge MA Aug 1995 - Dec 1996
-
Senior Scientist
Tufts University
Jan 1984 - Jan 1995
-
Assistant and Associate Professor of Large Animal Surgery
Education:
University of Pennsylvania 1978 - 1982
VMD, Veterinary Medicine Harvard Medical School 1977 - 1978
Post Doctoral Fellow, Muscle Physiology Harvard University 1972 - 1977
MS, PhD, Comparative Physiology Syracuse University 1968 - 1972
BSC, Biology
VMD, Veterinary Medicine Harvard Medical School 1977 - 1978
Post Doctoral Fellow, Muscle Physiology Harvard University 1972 - 1977
MS, PhD, Comparative Physiology Syracuse University 1968 - 1972
BSC, Biology
Interests:
pharmaceutical development, orthopedics, sports medicine, large animal surgery, running, kayaking, cross country skiing, hiking, biking, yoga, vintage autos, auto mechanics, orchids, music, bed and breakfasts, traveling, science fiction
Honor & Awards:
John Charnley Award Member, 2003 Hip Society
MGH Radiology Award Member, 2004
Scientific Presentation Award, International BMP meeting, 2002
Wyeth Research Team Award, 2001
Squibb Research Award, 1984
VOS Research Award, 1983
Mass Heart Association Post Doctoral Fellow Award, 1977-78
Harvard University Fellow, 1972-75
Syracuse University Biology Award, 1972
Phi Zeta Veterinary Honor Society, 1982
Calcium Phosphate Delivery Vehicles For Osteoinductive Proteins
US Patent:
8003133, Aug 23, 2011
Filed:
Sep 23, 2009
Appl. No.:
12/565159
Inventors:
Rebecca Li - Bedford MA, US
Howard Seeherman - Cambridge MA, US
Aliassghar Tofighi - Waltham MA, US
Howard Seeherman - Cambridge MA, US
Aliassghar Tofighi - Waltham MA, US
Assignee:
Wyeth LLC - Madison NJ
Etex Corporation - Cambridge MA
Etex Corporation - Cambridge MA
International Classification:
A61K 33/42, A61K 33/00
US Classification:
424601, 424717
Abstract:
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.
Injectable Calcium Phosphate Solid Rods And Pastes For Delivery Of Osteogenic Proteins
US Patent:
7771755, Aug 10, 2010
Filed:
Sep 10, 2004
Appl. No.:
10/937364
Inventors:
Rebecca Li - Bedford MA, US
Howard Seeherman - Cambridge MA, US
Hyun Kim - Bedford MA, US
Howard Seeherman - Cambridge MA, US
Hyun Kim - Bedford MA, US
Assignee:
Wyeth - Madison NJ
Etex Corporation - Cambridge MA
Etex Corporation - Cambridge MA
International Classification:
A61K 38/23, A61K 33/42
US Classification:
424602, 424499, 514 12, 530350
Abstract:
Osteogenic proteins are delivered via an injectable solid rod or hardenable paste. The formulation comprises a calcium phosphate material, an osteogenic protein, and optional additives and active ingredients such as a bone resorption inhibitor. Methods of making injectable pharmaceutical compositions and methods of using the osteogenic compositions to treat bone defects are also disclosed.
Calcium Phosphate Delivery Vehicles For Osteoinductive Proteins
US Patent:
7622139, Nov 24, 2009
Filed:
Dec 17, 2007
Appl. No.:
11/957691
Inventors:
Rebecca Li - Bedford MA, US
Howard Seeherman - Cambridge MA, US
Aliassghar Tofighi - Waltham MA, US
Howard Seeherman - Cambridge MA, US
Aliassghar Tofighi - Waltham MA, US
Assignee:
Wyeth - Madison NJ
ETEX Corporation - Cambridge MA
ETEX Corporation - Cambridge MA
International Classification:
A61K 33/42, A61K 33/02
US Classification:
424601, 424717
Abstract:
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.
Injectable Carrier Formulations Of Hyaluronic Acid Derivatives For Delivery Of Osteogenic Proteins
US Patent:
7608580, Oct 27, 2009
Filed:
Jan 18, 2007
Appl. No.:
11/624463
Inventors:
Hyun Kim - Middleton MA, US
Rebecca Li - Bedford MA, US
Alessandra Pavesio - Padua, IT
Lanfranco Callegaro - Thiene, IT
Howard Seeherman - Cambridge MA, US
John Wozney - Hudson MA, US
Rebecca Li - Bedford MA, US
Alessandra Pavesio - Padua, IT
Lanfranco Callegaro - Thiene, IT
Howard Seeherman - Cambridge MA, US
John Wozney - Hudson MA, US
Assignee:
Genetics Institute, LLC - Cambridge MA
Fidia Advanced Biopolymers S.R.L. - Abano Terme, Padua
Fidia Advanced Biopolymers S.R.L. - Abano Terme, Padua
International Classification:
A61K 38/16
US Classification:
514 2
Abstract:
An injectable formulation is disclosed for delivery of osteogenic proteins. The formulation comprises a pharmaceutically acceptable admixture of an osteogenic protein; and formulations comprising osteogenic protein, hyaluronic acid derivatives and tricalcium phosphate are also disclosed. Methods for formulating porous injectable gels and pastes from hyaluronic acid are also disclosed.
Bone Cement Mixing Systems And Related Methods
US Patent:
2008006, Mar 13, 2008
Filed:
Aug 29, 2007
Appl. No.:
11/846625
Inventors:
Martin Hughes - Wavendon, GB
Darren Seymour - Huntingdon, GB
Colin Turner - Girton, GB
Paul Harmer - Comberton, GB
Richard Cornell - Woburn MA, US
Howard Seeherman - Cambridge MA, US
Darren Seymour - Huntingdon, GB
Colin Turner - Girton, GB
Paul Harmer - Comberton, GB
Richard Cornell - Woburn MA, US
Howard Seeherman - Cambridge MA, US
Assignee:
WYETH - Madison NJ
International Classification:
A61B 17/58, A61M 31/00, A61M 5/178
US Classification:
606 93, 604 38, 604513, 606 94
Abstract:
Bone cement mixing systems and related methods are disclosed. The bone cement mixing systems can include a first chamber, a second chamber, and a passage fluidly connecting the first and second chambers. A first piston can be disposed in the first chamber, and a second piston can be disposed in the second chamber.
Calcium Phosphate Delivery Vehicles For Osteoinductive Proteins
US Patent:
7413753, Aug 19, 2008
Filed:
May 31, 2002
Appl. No.:
10/160607
Inventors:
Rebecca H. Li - Bedford MA, US
Howard Seeherman - Cambridge MA, US
Howard Seeherman - Cambridge MA, US
Assignee:
Wyeth - Madison NJ
Etex Corporation - Cambridge MA
Etex Corporation - Cambridge MA
International Classification:
A61K 33/42, A61K 9/14, A61K 9/50, A61K 33/00, A61K 38/00
US Classification:
424602, 424484, 424486, 424494, 424717, 514 2
Abstract:
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.
Use Of Sfrps As Markers Of Bmp Activity
US Patent:
2006016, Jul 27, 2006
Filed:
Jan 26, 2006
Appl. No.:
11/339549
Inventors:
Joanne Archambault - Medford MA, US
Scott Jelinsky - Waltham MA, US
Michael Agostino - Andover MA, US
Li Li - Watertown MA, US
Howard Seeherman - Cambridge MA, US
Scott Jelinsky - Waltham MA, US
Michael Agostino - Andover MA, US
Li Li - Watertown MA, US
Howard Seeherman - Cambridge MA, US
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
The disclosure provides assay systems for evaluating the presence of bone morphogenetic protein (BMP) activity in a cell by evaluating the gene expression of secreted Frizzled Related Protein 2 and 3 (sFRP2 and sFRP3). The sFRP2 and sFRP3 gene expression may be detected at the RNA or protein levels. The methods include methods for evaluating exogenous and endogenous BMP expression and utilize both genomic sFRP2 and sFRP3 genes and reporter constructs.
Use Of Fibrous Tissue Inducing Proteins For Hernia Repair
US Patent:
2007011, May 17, 2007
Filed:
Mar 23, 2006
Appl. No.:
11/386749
Inventors:
James Pickar - Springfield PA, US
Joanne Archambault - Arlington MA, US
Howard Seeherman - Cambridge MA, US
Joanne Archambault - Arlington MA, US
Howard Seeherman - Cambridge MA, US
International Classification:
A61K 38/18
US Classification:
514012000
Abstract:
The present disclosure relates to hernia repair and methods for stimulating growth of fascia tissue employing compositions comprising fibrous tissue inducing proteins.
Use Of Fibrous Tissue Inducing Proteins For Hernia Repair
US Patent:
2009015, Jun 18, 2009
Filed:
Feb 19, 2009
Appl. No.:
12/389171
Inventors:
James H. Pickar - Springfield PA, US
Joanne M. Archambault - Arlington MA, US
Howard Seeherman - Cambridge MA, US
Joanne M. Archambault - Arlington MA, US
Howard Seeherman - Cambridge MA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 38/02, A61B 17/03
US Classification:
514 2, 606151
Abstract:
The present disclosure relates to hernia repair and methods for stimulating growth of fascia tissue employing compositions comprising fibrous tissue inducing proteins.