HORNG H CHEN, M.D.
Osteopathic Medicine at 1 St, Rochester, MN
License number
Minnesota 38995
Category
Osteopathic Medicine
Type
Cardiovascular Disease
Address
Address
200 1St St SW, Rochester, MN 55905
Phone
(507) 284-2511
Professional information
Dr. Horng H Chen, Rochester MN - MD (Doctor of Medicine)
Specialties:
Cardiology, Advanced Heart Failure & Transplant Cardiology
Address:
Mayo Clinic
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
Procedures:
Cardiac Catheterization (incl. Coronary Angiography), Cardiac Imaging, Chest CT (incl. Heart and Lungs), Coronary Angioplasty, Atherectomy and Stent
Conditions:
Autonomic Disorders, Carotid Artery Disease, Endocarditis, Heart Attack (Acute Myocardial Infarction), Hyperlipidemia, Hypertension, Hypertensive Heart and Chronic Kidney Disease, Hypotension, Pericardial Disease, Pulmonary Hypertension, Pulmonary Valve Disease, Syncope, Tricuspid Valve Disease, Venous Hypertension
Certifications:
Advanced Heart Failure and Transplant Cardiology, 2012, Cardiovascular Disease, 2011, Internal Medicine, 1997
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Mayo Clinic
200 1St St SW, Rochester 55905
Mayo Clinic Saint Marys Hospital
1216 2Nd St South #West, Rochester 55902
200 1St St SW, Rochester 55905
Mayo Clinic Saint Marys Hospital
1216 2Nd St South #West, Rochester 55902
Education:
Medical School
Royal College of Surgeons In Ireland / Medical School
Mayo Grad School Med/Mayo Fndn
Royal College of Surgeons In Ireland / Medical School
Mayo Grad School Med/Mayo Fndn
Horng H Chen, Rochester MN
Specialties:
Cardiologist
Address:
200 1St St Sw, Rochester, MN 55905
Education:
Doctor of Medicine
Board certifications:
American Board of Internal Medicine Sub-certificate in Advanced Heart Failure and Transplant Cardiology (Internal Medicine), American Board of Internal Medicine Sub-certificate in Cardiovascular Disease (Internal Medicine)
Diuretic And Natriuretic Polypeptides Lacking The Blood Pressure Lowering Property
US Patent:
8324162, Dec 4, 2012
Filed:
Aug 8, 2007
Appl. No.:
12/376880
Inventors:
Robert D. Simari - Rochester MN, US
Shuchong Pan - Rochester MN, US
Horng H. Chen - Rochester MN, US
Shuchong Pan - Rochester MN, US
Horng H. Chen - Rochester MN, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
A61K 38/22, A61K 38/12, A61K 38/16, C07K 14/00, C12P 21/04, C12N 5/07
US Classification:
514 124, 514 213, 435 691, 435325, 530317, 530324, 536 235
Abstract:
This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.
Natriuretic Peptide Receptor-C Agonists
US Patent:
8357656, Jan 22, 2013
Filed:
Sep 15, 2008
Appl. No.:
12/677838
Inventors:
Robert D. Simari - Rochester MN, US
Shuchong Pan - Rochester MN, US
Horng H. Chen - Rochester MN, US
Lincoln R. Potter - Roseville MN, US
Shuchong Pan - Rochester MN, US
Horng H. Chen - Rochester MN, US
Lincoln R. Potter - Roseville MN, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
Regents of the University of Minnesota - Saint Paul MN
Regents of the University of Minnesota - Saint Paul MN
International Classification:
A61P 13/12, C07K 14/435
US Classification:
514 154, 530324
Abstract:
This document relates to methods and materials involved in preferentially activating natriuretic peptide receptor-C polypeptides. For example, agonists of natriuretic peptide receptor-C polypeptides as well as methods for activating natriuretic peptide receptor-C polypeptides are provided herein.
Natriuretic Polypeptides For Reducing Or Preventing Restenosis
US Patent:
8455438, Jun 4, 2013
Filed:
Dec 29, 2009
Appl. No.:
13/142537
Inventors:
Horng H. Chen - Rochester MN, US
Ondrej Lisy - Chattanooga TN, US
Ondrej Lisy - Chattanooga TN, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
C07K 14/58, C12P 21/04
US Classification:
514 124, 435 697
Abstract:
Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
Type V Phosphodiesterase Inhibitors And Natriuretic Polypeptides
US Patent:
2008003, Feb 7, 2008
Filed:
Aug 27, 2007
Appl. No.:
11/845535
Inventors:
John Burnett - Rochester MN, US
Horng Chen - Rochester MN, US
Horng Chen - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
A61K 38/18, A61K 31/519
US Classification:
514012000, 514252160, 514262100
Abstract:
This document provides methods and materials related to PDE V inhibitors, natriuretic polypeptides, and combinations thereof. For example, compositions containing one or more PDE V inhibitors in combination with one or more natriuretic polypeptides are provided herein. In addition, methods for using PDE V inhibitors, natriuretic polypeptides, and combinations thereof to influence heart or renal activities within a mammal are provided herein.
Chimeric Natriuretic Polypeptides And Methods For Inhibiting Cardiac Remodeling
US Patent:
2011015, Jun 23, 2011
Filed:
Jun 3, 2009
Appl. No.:
12/996500
Inventors:
Horng H. Chen - Rochester MN, US
Ondrej Lisy - Rochester MN, US
Ondrej Lisy - Rochester MN, US
International Classification:
A61K 38/16, A61P 9/10
US Classification:
514 164
Abstract:
Materials and methods related to chimeric polypeptides containing the amino acid sequence of CNP and the C-terminal sequence of DNP. The polypeptides are natriuretic and diuretic, GFR enhancing, cardiac unloading, renin inhibiting and less hypotensive when compared to BNP. The polypeptides also inhibit cardiac fibroblast proliferation.
Natriuretic Polypeptides Having Mutations Within Their Disulfide Rings
US Patent:
2012005, Mar 1, 2012
Filed:
May 5, 2010
Appl. No.:
13/266869
Inventors:
Horng H. Chen - Rochester MN, US
Assignee:
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH - Rochester MN
International Classification:
A61K 38/22, A61P 9/00, A61P 13/12, C07K 14/58, C07H 21/04, C12N 5/10, C12N 15/63, C07K 4/00
US Classification:
514 124, 4353201, 530300, 530324, 536 231, 435325
Abstract:
Materials and Methods related to making and using natriuretic polypeptides having a mutation in the ring portion of their structure.
Type V Phosphodiesterase Inhibitors And Natriuretic Polypeptides
US Patent:
2007004, Feb 22, 2007
Filed:
Aug 17, 2006
Appl. No.:
11/465380
Inventors:
John Burnett - Rochester MN, US
Horng Chen - Rochester MN, US
Horng Chen - Rochester MN, US
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
A61K 38/17, A61K 31/519
US Classification:
514012000, 514252160
Abstract:
This document provides methods and materials related to PDE V inhibitors, natriuretic polypeptides, and combinations thereof. For example, compositions containing one or more PDE V inhibitors in combination with one or more natriuretic polypeptides are provided herein. In addition, methods for using PDE V inhibitors, natriuretic polypeptides, and combinations thereof to influence heart or renal activities within a mammal are provided herein.
Natriuretic Polypeptides For Reducing Or Preventing Restenosis
US Patent:
2013028, Oct 24, 2013
Filed:
May 7, 2013
Appl. No.:
13/888906
Inventors:
Horng H. Chen - Rochester MN, US
Ondrej Lisy - Chattanooga TN, US
Ondrej Lisy - Chattanooga TN, US
International Classification:
C07K 14/58
US Classification:
514 124
Abstract:
Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.