Inventors:
Anand Swaroop - Ann Arbor MI, US
Masayuki Akimoto - Kyoto, JP
Alan Mears - Ottawa, CA
Hong Cheng - Ann Arbor MI, US
Edwin C.T. Oh - Baltimore MD, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
C12Q 1/68, C12N 5/07, C12N 15/00
Abstract:
The present invention relates to photoreceptor cells. In particular, the present invention provides photoreceptor cells comprising heterologous nucleic acid sequences and transgenic animals comprising the same. The present invention also provides photoreceptor precursor cells (e.g., rod photoreceptor precursor cells), and methods of identifying, characterizing, isolating and utilizing the same. Compositions and methods of the present invention find use in, among other things, research, clinical, diagnostic, drug discovery, and therapeutic applications.