Inventors:
Henry Kaminski - Washington DC, US
Linda Kusner - Washington DC, US
Namita Satija - St. Louis MO, US
International Classification:
A61K 38/17, A61P 21/04, A61P 21/00, C07K 19/00, A61K 39/44
US Classification:
4241351, 514 177, 5303919
Abstract:
Compositions and methods for targeting therapeutic agents to neuromuscular junctions are disclosed. Also disclosed are methods for treating diseases and conditions affecting the neuromuscular junction. Compositions include a neuromuscular junction targeting peptide coupled to a therapeutic agent. Compositions may further include a linker peptide. Methods for targeting therapeutic agents to neuromuscular junctions and treating diseases and conditions affecting the neuromuscular junction include administering a composition including a neuromuscular junction targeting peptide coupled to a therapeutic agent.