DR. HELENE F ROSENBERG, M.D.
Medical Practice at Greentree Rd, Bethesda, MD
License number
Maryland 57727
Category
Medical Practice
Type
Research Study
Address
Address
5607 Greentree Rd, Bethesda, MD 20817
Phone
(301) 402-1545
Professional information
Dr. Helene F Rosenberg, Bethesda MD - MD (Doctor of Medicine)
Specialties:
Infectious Disease Medicine
Address:
9000 Rockville Pike, Bethesda 20892
(301) 402-1545 (Phone)
(301) 402-1545 (Phone)
Languages:
English
Education:
Medical School
Weill Cornell Medical College
Graduated: 1985
Weill Cornell Medical College
Graduated: 1985
Methods For Inactivating Enveloped Rna Virus Particles And Compositions For Use Therewith
US Patent:
6426070, Jul 30, 2002
Filed:
May 9, 2000
Appl. No.:
09/446959
Inventors:
Helene F. Rosenberg - Bethesda MD
Joseph B. Domachowske - Syracuse NY
Joseph B. Domachowske - Syracuse NY
Assignee:
The United States as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 3847
US Classification:
424 9461, 4241851, 4242111, 436 692, 436238, 530350, 530380
Abstract:
A method for inactivating a virion of an enveloped RNA virus comprising contacting the virion with an eosinophil-derived ribonuclease, such as eosinophil-derived neurotoxin (EDN) or eosinophil cationic protein (ECP). The invention also provides methods for treating a subject infected by an enveloped RNA virus and for preventing infection by an enveloped RNA virus comprising administering an effective amount of an eosinophil-derived ribonuclease, such as EDN or ECP. The invention also provides a composition comprising an effective amount of an eosinophil-derived ribonuclease and an acceptable carrier.
Rnase A Peptides, Fragments And Uses Thereof
US Patent:
2010030, Dec 2, 2010
Filed:
Aug 24, 2007
Appl. No.:
12/438700
Inventors:
Takeaki Nitto - Saga, JP
Kimberly D. Dyer - Reston VA, US
Meggan Czapiga - Bethesda MD, US
Helene F. Rosenberg - Bethesda MD, US
Steven J. Siegel - Rockville MD, US
Kimberly D. Dyer - Reston VA, US
Meggan Czapiga - Bethesda MD, US
Helene F. Rosenberg - Bethesda MD, US
Steven J. Siegel - Rockville MD, US
Assignee:
Government of the US, as represented by the Secretary, Department of Health and Human Services - Rockville MD
International Classification:
A61K 38/17, C07H 21/04, C07K 14/00, C07K 16/40, C07K 7/06, C12N 9/22, C07K 7/08, A61P 31/04
US Classification:
514 24, 536 231, 536 235, 530350, 5303891, 530328, 435199, 530326, 514 135
Abstract:
The present invention features isolated polypeptides that have bactericidal and angiogenic activities. The invention features isolated polypeptides comprising amino acid sequences of RNase A ribonucleases, fragments and variants thereof, pharmaceutical compositions, and methods for treatment of a subject.
Compositions And Methods For Enhancing An Immune Response
US Patent:
2006000, Jan 12, 2006
Filed:
Apr 29, 2004
Appl. No.:
10/834733
Inventors:
De Yang - Frederick MD, US
Joost Oppenheim - Bethesda MD, US
Helene Rosenberg - Bethesda MD, US
Joost Oppenheim - Bethesda MD, US
Helene Rosenberg - Bethesda MD, US
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
The invention provides compositions and methods of enhancing an immune response in a subject. The compositions comprise eosinophil derived-neurotoxin (EDN) and/or human pancreatic ribonuclease (hPR), which can be used as adjuvants to elicit an enhanced immune response in a subject.