DR. HEEJIN MICHELLE KIM, M.D.
Osteopathic Medicine at Saddle Rd, Cedar Knolls, NJ
License number
New Jersey 25MA09788700
Category
Osteopathic Medicine
Type
Pulmonary Disease
License number
New Jersey 25MA09788700
Category
Osteopathic Medicine
Type
Critical Care Medicine
Address
Address
2
8 Saddle Rd SUITE 101, Cedar Knolls, NJ 07927
PO Box 416457, Boston, MA 02241
PO Box 416457, Boston, MA 02241
Phone
(973) 267-9393
(973) 656-6280
(973) 290-7495 (Fax)
(973) 656-6280
(973) 290-7495 (Fax)
Professional information
Processes For The Preparation Of Hydroxylamines
US Patent:
7919627, Apr 5, 2011
Filed:
Jun 9, 2008
Appl. No.:
12/135299
Inventors:
Datong Tang - Watertown MA, US
Yao-Ling Qiu - Andover MA, US
Heejin Kim - Allston MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Yao-Ling Qiu - Andover MA, US
Heejin Kim - Allston MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Assignee:
Enanta Pharmaceuticals, Inc. - Watertown MA
International Classification:
C07D 401/04
US Classification:
5462754
Abstract:
The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia):.
6-11 Bicyclic Ketolide Derivatives
US Patent:
2009032, Dec 31, 2009
Filed:
Jun 29, 2009
Appl. No.:
12/493847
Inventors:
Yat Sun Or - Watertown MA, US
Wang Guoqiang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
Wang Guoqiang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
International Classification:
A61K 31/7048, C07H 17/08, A61P 31/04
US Classification:
424114, 536 71, 514 29
Abstract:
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
Processes For The Preparation Of O-(6-Pyrazol-1-Yl-Pyridin-3-Ylmethyl)-Hydroxylamine
US Patent:
7538225, May 26, 2009
Filed:
Aug 17, 2005
Appl. No.:
11/205764
Inventors:
Datong Tang - Watertown MA, US
Yao-Ling Qiu - Andover MA, US
Heejin Kim - Allston MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Yao-Ling Qiu - Andover MA, US
Heejin Kim - Allston MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Assignee:
Enanta Pharmaceuticals, Inc. - Watertown MA
International Classification:
C07D 401/04
US Classification:
5462754
Abstract:
The present invention relates generally to novel methods for the synthesis of O-(6-pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine which is an essential reagent in the synthesis of one of the bridged erythromycin derivatives and their respective pharmaceutically acceptable salts in PCT Application WO 03/097659 A1. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (Ia):.
C-8 Halogenated Macrolides
US Patent:
2009020, Aug 20, 2009
Filed:
Feb 13, 2009
Appl. No.:
12/370805
Inventors:
IN JONG KIM - LEXINGTON MA, US
GUOQIANG WANG - BELMONT MA, US
HEEJIN KIM - ALLSTON MA, US
YAT SUN OR - WATERTOWN MA, US
GUOQIANG WANG - BELMONT MA, US
HEEJIN KIM - ALLSTON MA, US
YAT SUN OR - WATERTOWN MA, US
International Classification:
A61K 31/4985, A61K 31/4375, A61K 31/4439, A61K 31/424, C07D 471/04, C07D 498/04
US Classification:
514250, 514300, 514338, 514375, 544350, 546122, 5462717, 548218
Abstract:
The present invention discloses compounds of formula (I) or pharmaceutically acceptable salts, esters, or prodrugs thereof:which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
Processes For The Preparation Of O-(6-Pyrazol-1-Yl-Pyridin-3-Ylmethyl)-Hydroxylamine
US Patent:
7135573, Nov 14, 2006
Filed:
Oct 25, 2005
Appl. No.:
11/257680
Inventors:
Heejin Kim - Allston MA, US
Guoqiang Wang - Belmont MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Guoyou Xu - Newton MA, US
Ly Tam Pham - Quincy MA, US
Guoqiang Wang - Belmont MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Guoyou Xu - Newton MA, US
Ly Tam Pham - Quincy MA, US
Assignee:
Enanta Pharmaceuticals, Inc. - Watertown MA
International Classification:
C07D 237/02, A61K 31/7052
US Classification:
5462754, 514 29
Abstract:
The present invention relates to processes and intermediates for the preparation of 6–11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (IX-c):.
Bridged Carbamate Macrolides
US Patent:
2008002, Jan 31, 2008
Filed:
Jul 24, 2007
Appl. No.:
11/781985
Inventors:
Heejin Kim - Allston MA, US
Ly Tam Phan - Quincy MA, US
Yat Or - Watertown MA, US
Ly Tam Phan - Quincy MA, US
Yat Or - Watertown MA, US
International Classification:
A61K 31/7048, A61P 31/00, C07H 17/08
US Classification:
514028000, 536007100
Abstract:
The present invention discloses compounds of formulae (I) and (II) or pharmaceutically acceptable salts, esters, or prodrugs thereof:
which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
6-11 Bicyclic Ketolide Derivatives
US Patent:
2007024, Oct 18, 2007
Filed:
Jun 5, 2007
Appl. No.:
11/758225
Inventors:
Yat Sun Or - Watertown MA, US
Wang Guoqiang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
Wang Guoqiang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
International Classification:
A61K 31/44, A61P 31/04
US Classification:
514333000, 546256000
Abstract:
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:
which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention. The invention further includes process by which to make the compounds of the present invention.
Processes For The Preparation Of 6-11 Bicyclic Erythromycin Derivatives
US Patent:
7022679, Apr 4, 2006
Filed:
Jan 14, 2004
Appl. No.:
10/758409
Inventors:
Heejin Kim - Allston MA, US
Guoqiang Wang - Belmont MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Guoqiang Wang - Belmont MA, US
Yat Sun Or - Watertown MA, US
Zhe Wang - Hockessin DE, US
Assignee:
Enanta Pharmaceuticals, Inc. - Watertown MA
International Classification:
C07H 17/08
US Classification:
514 29, 536 74, 536 185
Abstract:
The present invention relates to processes and intermediates for the preparation of 6–11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (IX-c):.
6-11 Bicyclic Ketolide Derivatives
US Patent:
7273853, Sep 25, 2007
Filed:
Jan 25, 2005
Appl. No.:
11/042720
Inventors:
Yat Sun Or - Watertown MA, US
Guoqiang Wang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
Guoqiang Wang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
Assignee:
Enanta Pharmaceuticals, Inc. - Watertown MA
International Classification:
A61K 31/70, C07H 17/08
US Classification:
514 29, 536 72, 536 74
Abstract:
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:.
6-11 Bicycle Ketolide Derivatives
US Patent:
7064110, Jun 20, 2006
Filed:
Nov 19, 2003
Appl. No.:
10/717290
Inventors:
Yat Sun Or - Watertown MA, US
Wang Guoqiang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
Wang Guoqiang - Belmont MA, US
Ly Tam Phan - Quincy MA, US
Deqiang Niu - Lexington MA, US
Nha Huu Vo - Southborough MA, US
Yao-Ling Qiu - Andover MA, US
Yanchun Wang - Somerville MA, US
Marina Busuyek - Natick MA, US
Ying Hou - Everett MA, US
Yulin Peng - Belmont MA, US
Heejin Kim - Allston MA, US
Tongzhu Liu - Auburndale MA, US
Jay Judson Farmer - New Haven CT, US
Guoyou Xu - Auburndale MA, US
Assignee:
Enanta Pharmaceuticals, Inc. - Watertown MA
International Classification:
A61K 31/70, C07H 17/08
US Classification:
514 29, 536 74
Abstract:
The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof:.