Inventors:
Cesar E. Guerra - Guilford CT, US
Michelle Dunham Guerra - Guilford CT, US
Harvey L. Ozer - Hoboken NJ, US
Assignee:
University of Medicine & Dentistry of New Jersey - Somerset NJ
International Classification:
C12N 15/85, C12P 19/34, C12N 5/10, C12P 21/00
US Classification:
435 691, 4353201, 435 913, 435363, 435367, 435358, 435325
Abstract:
The invention relates to a vector comprising an origin of replication for episomal maintenance in a metazoan cell, a gene for episomal maintenance in the metazoan cell, and a telomeric polynucleotide sequence. The vector can be used for episomal expression of RNA and polypeptides in metazoan cells.