Inventors:
Darren Schofield - Royston, GB
Suzanne U. Emerson - Kensington MD, US
Robert H. Purcell - Boyds MD, US
Harvey J. Alter - Chevy Chase MD, US
Assignee:
The United States of America as represented by the Department of Health & Human Services - Washington DC
International Classification:
C07K016/00, A61K039/395, A61K039/42, C12Q001/70, G01N033/53
US Classification:
5303883, 5303871, 5303881, 4241411, 4241471, 4241491, 435 5, 435 71, 435 691
Abstract:
The present invention describes the identification and characterization of five human HC E1-specific monoclonal antibodies isolated from a phage display library and their use in the diagnosis, treatment, and prevention of HCV in mammals, preferably humans.