HARVEY J KLIMAN, MD
Medical Practice at Sargent Dr, New Haven, CT

6733962, May 11, 2004

Mar 8, 2001

09/801470

Harvey J. Kliman - New Haven CT 06525
Rebecca L. Dubowy - Chicago IL

Harvey J. Kliman - New Haven CT

C12Q 100

435 4, 435 71

Methods of diagnosing an abnormality in endometrial glandular development in a woman suspected of being infertile are disclosed. Methods of predicting abnormal endometrial glandular development are also disclosed. In addition, methods of assessing the suitability of the endometrium for embryo implantation in a woman undergoing ovulation induction are disclosed. Further, methods of evaluating the effect of a hormonal protocol on endometrial glandular development in a woman undergoing a hormonal protocol to produce a mock cycle are disclosed. Methods of evaluating a hormone replacement therapy protocol in a woman undergoing hormone replacement therapy are disclosed. Further, methods of diagnosing endometrial glandular mitotic arrest in a woman suspected of having endometrial hyperplasia are disclosed.

2008002, Jan 31, 2008

Jul 31, 2006

11/496660

Harvey J. Kliman - Woodbridge CT, US

A61B 10/00

600562

Biologic information is obtained concerning a member of a population by obtaining a tissue sample from the member, storing the sample without embedding it in an embedding medium, retrieving from storage the sample associated with the member and thereafter analyzing it for biologic information. The tissue sample may be all or part of the member's placenta. Storage may be in a fixative such as formalin or a formalin substitute. Storage may also be by other means of preserving such as freezing or the like. When a tissue sample from more than one member is collected, a library is created that may be used for a variety of purposes, including reducing the incidence of medical malpractice claims, identification of members such as paternity testing or suspect identification. The library may also be used for pharmaceutical development and epidemiological surveys and research. Each sample may have associated with it certain epidemiologic information such as the donor's identity and medical history, residence, place of employment and the like. If the sample is of placental tissue similar information concerning the member's parents may also be recorded, as well as the hospital where the delivery occurred, the attending physician's name and the like. If and when a sample is retrieved and analyzed for biologic information, that information may also be associated with the sample so that it is available for future researchers.

2013030, Nov 14, 2013

Jul 19, 2013

13/946394

HARVEY J. KLIMAN - WOODBRIDGE CT, US

G01N 1/30

435 61, 435325, 435 4052

Biologic information is obtained concerning a member of a population by obtaining a sample of placental tissue from the member, storing the sample without embedding it in an embedding medium, retrieving from storage the sample associated with the member and thereafter analyzing it for biologic information. Storage may be in a fixative such as formalin or a formalin substitute. When a tissue sample from more than one member is collected, a library is created that may be used for a variety of purposes, including reducing the incidence of medical malpractice claims, identification of members such as paternity testing or suspect identification, pharmaceutical development and epidemiological surveys and research.

5693479, Dec 2, 1997

Dec 13, 1994

8/354671

Ronald F. Feinberg - Cherry Hill NJ
Harvey Jon Kliman - Woodbridge CT

The Trustees of the University of Pennsylvania - Philadelphia PA
The Trustees of Yale University - New Haven CT

G01N 33567, G01N 33577

435 721

Therapeutic and diagnostic methods of use for the growth factor transforming growth factor. beta. , are provided by this invention. In accordance with preferred embodiments, methods of determining competence of a conceptus toward uterine implantation are provided as are methods for determining female infertility in mammals.

5395825, Mar 7, 1995

Mar 10, 1993

8/029027

Ronald F. Feinberg - Cherry Hill NJ
Harvey J. Kliman - Woodbridge CT

Yale University - New Haven CT
Trustees of the University of Pennsylvania - Philadelphia PA

A61K 3702, A61B 17425, A61B 17435, A61D 1904

514 21

Therapeutic and diagnostic methods of use for the growth factor transforming growth factor. beta. , are provided by this invention. In accordance with preferred embodiments, methods of determining and improving competence of a conceptus toward uterine implantation are provided as are methods for determining female infertility in mammals.

5523229, Jun 4, 1996

Mar 22, 1994

8/215906

Ronald F. Feinberg - Cherry Hill NJ
Harvey J. Kliman - Woodbridge CT

Trustees of the University of Pennsylvania - Philadelphia PA

C12N 512, C07K 1618, C07K 1478, G01N 3353

43524027

Immunologic binding partners which specifically bind to oncofetal fibronectin but not normal adult fibronectin or blood plasma fibronectin and methods of diagnosing and treating oncogenesis and reproductive abnormalities employing the same.

2009032, Dec 31, 2009

Feb 1, 2008

12/524569

Harvey Kliman - Woodbridge CT, US

A61B 8/14, A61B 5/107

600443

Method and system for determining a volume of a placenta in utero. The placenta in utero may be modeled as having a convex-concave shape (e.g., like that of a portion of a spherical shell). Volume of the placenta may be determined based on the width (or height) and thickness of the placenta, or based on width, height and thickness of the placenta. Placenta size characteristics may be measured using imaging techniques, such as ultrasound. In one aspect of the invention, a volume of a placenta in utero may be compared to the volume of other placentas for similar gestational age, and a determination regarding whether the placenta volume poses a risk to fetal health may be made.