Inventors:
Gunnar E. Jagdmann - Durham NC
Harry R. Munson - Durham NC
Assignee:
A. H. Robins Company, Incorporated - Richmond VA
International Classification:
A61K 31435, C07D22102
Abstract:
Novel 1-(azabicyclo[2. 2. 2]oct-3- or -4-yl)benzamides substituted on the benzene ring with the basic substituted aminomethyleneamino group have been found to be useful in treating emesis, including emesis due to chemical and radiation anticancer therapy, anxiety, and impaired gastric emptying. These compounds are represented by Formula I below. ##STR1##.