Inventors:
Linda Arterburn - Ellicott City MD, US
James Hoffman - Blue Bell PA, US
Harry Oken - Columbia MD, US
Mary Van Elswyk - Longmont CO, US
Assignee:
Martek Biosciences Corporation - Columbia MD
International Classification:
A61K 31/202, A61P 29/00, A61K 31/60, A61K 31/4365, A61P 3/00
Abstract:
This invention is directed to methods and compositions which impede the development and progression of diseases associated with subclinical inflammation. Subclinical inflammation is commonly associated with atherosclerotic cardiovascular disease, coronary disease or cerebrovascular disease. The methods and compositions of the invention are also particularly suited to providing therapy for subclinical inflammation in diabetic and prediabetic patients. Methods of the invention comprise administration of DHA alone and in combination with antiplatelet drugs.