HARRIET MARGOT KLUGER, MD
Osteopathic Medicine in New Haven, CT

License number

Connecticut 038926

Personal information

See more information about HARRIET MARGOT KLUGER at radaris.com

Name

Address

Phone

Harriet M Kluger, age 59

26 Hemlock Hollow Rd, Woodbridge, CT 06525

(203) 389-5779

Professional information

See more information about HARRIET MARGOT KLUGER at trustoria.com

Melanoma Prognostic Model Using Tissue Microarrays And Genetic Algorithms

US Patent:

2012027, Oct 25, 2012

Filed:

Oct 29, 2010

Appl. No.:

13/505240

Inventors:

David L. Rimm - Branford CT, US
Aaron J. Berger - Mountain View CA, US
Bonnie Rothberg - Guilford CT, US
Robert L. Camp - San Francisco CA, US
Harriet Kluger - Woodbridge CT, US

International Classification:

G01N 33/574, G01N 21/64

US Classification:

435 723

Abstract:

The invention provides a method for determining the risk that a patient diagnosed with melanoma will develop a recurrence of melanoma comprising: a) determining the level of expression for each marker of a panel of markers, wherein the panel comprises activating transcription factor 2, p21, p16, β-catenin, and fibronectin and the levels of expression are determined in compartments of interest in cells of interest in a tumor tissue sample from the patient; and b) determining whether an expression parameter for each marker in the tumor tissue sample is achieved by comparing the level of expression of each marker with a predetermined reference level associated with each marker; wherein the patient is at a low risk of developing a recurrence of melanoma if four or more of the expression parameters are achieved and wherein the patient is at a high risk of developing a recurrence of melanoma if three or fewer of the expression parameters are achieved.

Dr. Harriet M Kluger, New Haven CT - MD (Doctor of Medicine)

Specialties:

Oncology, Medical Oncology

Address:

Smilow Cancer Hospital
35 Park St, New Haven 06519
(203) 688-4242 (Phone)
Milo Multispecialty Care Center
35 Park St, New Haven 06519
(203) 785-4191 (Phone)

Certifications:

Internal Medicine, 1997, Medical Oncology, 2012

Awards:

Healthgrades Honor Roll

Languages:

English, Hebrew

Hospitals:

Smilow Cancer Hospital
35 Park St, New Haven 06519
Milo Multispecialty Care Center
35 Park St, New Haven 06519
Yale - New Haven Hospital
20 York St, New Haven 06510

Education:

Medical School
Tel Aviv University / Sackler Faculty of Medicine
U New Mexico
Highland Genl Hosp

Harriet Margot Kluger, New Haven CT

Specialties:

Oncologist

Address:

333 Cedar St, New Haven, CT 06510
20 York St, New Haven, CT 06510

Education:

Tel Aviv University, Sackler School of Medicine - Doctor of Medicine*
Alameda County Medical Center-Highland Hospital - Residency - Internal Medicine*
Children's Hospital of New Mexico - Residency - Internal Medicine*

Board certifications:

American Board of Internal Medicine Sub-certificate in Oncology (Internal Medicine)*

Harriet M Kluger, New Haven CT

Specialties:

Internal Medicine, Medical Oncology

Work:

Yale University
800 Howard Ave, New Haven, CT 06519

Education:

Sackler School Of Medicine (1993)

Combination Chemotherapy Compositions And Methods

US Patent:

2008006, Mar 20, 2008

Filed:

Apr 5, 2007

Appl. No.:

11/730985

Inventors:

Graham Kelly - Northbridge, AU
Alan Husband - McMahon's Point, AU
David Brown - North Ryde, AU
Harriet Kluger - New Haven CT, US
Gil Mor - New Haven CT, US

International Classification:

A61K 31/437, A61K 31/05, A61K 31/12, A61K 31/337, A61P 35/00, C12N 5/06, A61K 33/24, A61K 31/352, A61K 31/397

US Classification:

424649000, 435375000, 514184000, 514210160, 514283000, 514456000, 514679000, 514734000

Abstract:

This invention relates to combination therapies involving anticancer chemotherapeutic agents and isoflavones or analogues thereof. The invention flier relates to compounds, compositions, methods and therapeutic uses involving, containing, comprising, including and/or for preparing platinum-isoflavonoid complexes suitable for use in the combination therapies of the invention.