Inventors:
Gregory Scott Retzinger - Cincinnati OH
Ashley P. Deanglis - Cincinnati OH
Assignee:
University of Cincinnati - Cincinnati OH
International Classification:
A61K 9127
Abstract:
A method for preparing fibrinogen-coated liposomes is disclosed. In this process, fibrinogen and an acylating agent are reacted in the presence of a dispersion of liposomes under specifically defined reaction conditions. The liposomes formed using this process, pharmaceutical compositions containing those liposomes, and the methods of clotting blood and delivering pharmaceutically-active agents and/or other chemicals utilizing those pharmaceutical compositions are also disclosed.