Inventors:
Jingwu Duan - Newark DE
Gregory Ott - Philadelphia PA
Lihua Chen - Wilmington DE
Carl Decicco - Kennett Square PA
Zhonghui Lu - Wilmington DE
Assignee:
Bristol-Myers Squibb Pharma Company - Princeton NJ
International Classification:
A61K 3147
Abstract:
The present application describes novel cyclic -amino acid derivatives of formula I: or pharmaceutically acceptable salt forms thereof, wherein ring B is a 5-7 membered cyclic system containing from 0-2 heteroatoms selected from O, N, NR , and S(O) , and 0-1 carbonyl groups and the other variables are defined in the present specification, which are useful as metalloprotease and/or as TNF- inhibitors.