Inventors:
Javier R. Echauz - Alpharetta GA, US
Gregory A. Worrell - Rochester MN, US
Brian Litt - Bala Cynwyd PA, US
Assignee:
The Trustees Of The University Of Pennsylvania - Philadelphia PA
International Classification:
A61N 1/18
US Classification:
607 45, 607 46, 607 47, 607 48
Abstract:
Developing a measure of critical systems-like behavior in an epilepsy patient in order to map epileptic networks, either passively or evoking responses through subthreshold stimulation, and to apply “therapeutic” stimulations to the patient that cause smaller, but more frequent dissipations of “energy,” a transcription product, subclinical electrophysiological activity or seizures in order to raise the clinical seizure initiation threshold, through releasing accumulated interictal energy in a seizure onset zone or elsewhere in the epileptic network, thereby preventing occurrence of larger more debilitating seizures.