GREGG SEMENZA, M.D.
Medical Practice at Caroline St, Baltimore, MD
License number
Maryland D40020
Category
Medical Practice
Type
Pediatrics
Address
Address
601 N Caroline St, Baltimore, MD 21287
Phone
(410) 955-3071
Personal information
See more information about GREGG SEMENZA at radaris.comName
Address
Phone
13026 Heil Manor Dr, Reisterstown, MD 21136
Towson, MD
13026 Heil Manor Dr, Reisterstown, MD 21136
718 Scarlett Dr, Towson, MD 21286
Organization information
See more information about GREGG SEMENZA at bizstanding.comGregg Semenza MD
600 N Wolfe St, Baltimore, MD 21287
Industry:
Genetic Medicine, Pediatrician
Phone:
(410) 955-2000 (Phone)
Gregg Leonard Semenza
Professional information
See more information about GREGG SEMENZA at trustoria.com
Professor At Johns Hopkins School Of Medicine
Professor At Johns Hopkins School Of Medicine
Position:
Professor at Johns Hopkins School of Medicine
Location:
Baltimore, Maryland Area
Industry:
Research
Work:
Johns Hopkins School of Medicine
-
Professor
Dr. Gregg Semenza, Baltimore MD - MD (Doctor of Medicine)
Dr. Gregg Semenza, Baltimore MD - MD (Doctor of Medicine)
Specialties:
Pediatrics, Clinical Genetics
Address:
Baltimore Office
601 N Caroline St, Baltimore 21287
(410) 955-3071 (Phone), (410) 955-6526 (Fax)
BROADWAY RESEARCH BUILDING
733 N Broadway SUITE 671, Baltimore 21205
(410) 955-1619 (Phone), (410) 614-9568 (Fax)
601 N Caroline St, Baltimore 21287
(410) 955-3071 (Phone), (410) 955-6526 (Fax)
BROADWAY RESEARCH BUILDING
733 N Broadway SUITE 671, Baltimore 21205
(410) 955-1619 (Phone), (410) 614-9568 (Fax)
Certifications:
Clinical Genetics, 1990, Pediatrics, 1989
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Perelman School of Medicine University of Pennsylvania
Graduated: 1984
Duke University Med Center
Johns Hopkins Hospital
Perelman School of Medicine University of Pennsylvania
Graduated: 1984
Duke University Med Center
Johns Hopkins Hospital
Gregg Leonard Semenza, Baltimore MD
Gregg Leonard Semenza, Baltimore MD
Specialties:
Pediatrics, Clinical Genetics, M.D.
Work:
Johns Hopkins University
600 N Wolfe St, Baltimore, MD 21287
600 N Wolfe St, Baltimore, MD 21287
Education:
University of Pennsylvania(1984)
Stable Hypoxia Inducible Factor-1 And Method Of Use
Stable Hypoxia Inducible Factor-1 And Method Of Use
US Patent:
6562799, May 13, 2003
Filed:
Aug 25, 1999
Appl. No.:
09/383581
Inventors:
Gregg L. Semenza - Towson MD
Assignee:
The Johns Hopkins University School of Medicine - Baltimore MD
International Classification:
A61K 3170
US Classification:
514 44, 4353201, 435455, 435375, 435471, 536 231, 536235
Abstract:
Substantially purified stable human hypoxia-inducible factor-1 (sHIF-1alpha) proteins and polynucleotides encoding stable human hypoxia-inducible factor-1 proteins are provided. A method is provided for treating a hypoxia-related tissue damage in a subject by administering to the subject a therapeutically effective amount of a sHIF-1alpha protein or a nucleic acid encoding a stable HIF-1alpha protein. Formulations are provided for the administration of stable human hypoxia inducible factor-1 (HIF-1alpha) polypeptide or a polynucleotide encoding stable human hypoxia inducible factor-1alpha (HIF-1alpha) to a patient having or at risk of having hypoxia- or ischemia-related tissue damage.
Mutant Hypoxia Inducible Factor-1 Hif-1
Mutant Hypoxia Inducible Factor-1 Hif-1
US Patent:
6124131, Sep 26, 2000
Filed:
Aug 25, 1998
Appl. No.:
9/148547
Inventors:
Gregg L. Semenza - Towson MD
Assignee:
The Johns Hopkins University School of Medicine - Baltimore MD
International Classification:
C07K 1600, C12N 1512, C12N 1574, C12N 1585
US Classification:
435325
Abstract:
Substantially purified stable human hypoxia-inducible factor-1. alpha. (sHIF-1. alpha. ) mutein is provided. Polynucleotides encoding stable human hypoxia-inducible factor-1. alpha. mutein are also provided. A method is provided for treating a hypoxia-related tissue damage in a subject by administering to the subject a therapeutically effective amount of a sHIF-1. alpha. mutein or a nucleotide sequence including an expression control sequence operatively linked to a polynucleotide encoding a stable hypoxia-inducible factor-1. alpha. mutein. Formulations are provided for the administration of stable human hypoxia inducible factor-1. alpha. (HIF-1. alpha. ) polypeptide or a polynucleotide encoding stable human hypoxia inducible factor-1. alpha. (HIF-1. alpha. ) to a patient having hypoxia-related tissue damage.
Nucleic Acids Encoding The Hypoxia Inducible Factor-1
Nucleic Acids Encoding The Hypoxia Inducible Factor-1
US Patent:
6020462, Feb 1, 2000
Filed:
Aug 20, 1997
Appl. No.:
8/915213
Inventors:
Gregg L. Semenza - Towson MD
Assignee:
The Johns Hopkins University School of Medicine - Baltimore MD
International Classification:
C07K 14435, C12N 1512
US Classification:
530350
Abstract:
The purified and characterization of hypoxia-inducible factor 1 (HIF-1) is described. HIF-1 is composed of subunits HIF-1a and HIF-1. beta. Purified HIF-1a polypeptide, its amino acid sequence and polynucleotide sequence are provided. A HIF-1. alpha. variant that dimerizes to HIF-1. beta. producing a nonfunctional HIF-1 complex is described. Methods for the prevention and treatment of hypoxia-related disorders are provided.
Stable Hypoxia Inducible Factor-1 Alpha And Method Of Use
Stable Hypoxia Inducible Factor-1 Alpha And Method Of Use
US Patent:
2003017, Sep 18, 2003
Filed:
Apr 25, 2003
Appl. No.:
10/423419
Inventors:
Gregg Semenza - Towson MD, US
International Classification:
A61K038/18, C12P021/02, C12N005/06, C07K014/475
US Classification:
514/012000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023200
Abstract:
Substantially purified stable human hypoxia-inducible factor-1 (sHIF-1alpha) proteins and polynucleotides encoding stable human hypoxia-inducible factor-1 proteins are provided. A method is provided for treating a hypoxia-related tissue damage in a subject by administering to the subject a therapeutically effective amount of a sHIF-1alpha protein or a nucleic acid encoding a stable HIF-1alpha protein. Formulations are provided for the administration of stable human hypoxia inducible factor-1 (HIF-1alpha) polypeptide or a polynucleotide encoding stable human hypoxia inducible factor-1alpha (HIF-1alpha) to a patient having or at risk of having hypoxia- or ischemia-related tissue damage.
Hypoxia Inducible Factor-1 And Method Of Use
Hypoxia Inducible Factor-1 And Method Of Use
US Patent:
6222018, Apr 24, 2001
Filed:
Jan 22, 1999
Appl. No.:
9/235217
Inventors:
Gregg L. Semenza - Towson MD
Assignee:
The Johns Hopkins University School of Medicine - Baltimore MD
International Classification:
C07K 1618
US Classification:
5303871
Abstract:
The purified and characterization of hypoxia-inducible factor 1 (HIF-1) is described. HIF-1 is composed of subunits HIF-1. alpha. and HIF-1. beta. Purified HIF-1. alpha. polypeptide, its amino acid sequence and polynucleotide sequence are provided. A HIF-1. alpha. variant that dimerizes to HIF-1. beta. producing a nonfunctional HIF-1 complex is described. Methods for the prevention and treatment of hypoxia-related disorders are provided.
Nucleic Acids Encoding The Hypoxia Inducible Factor-1
Nucleic Acids Encoding The Hypoxia Inducible Factor-1
US Patent:
5882914, Mar 16, 1999
Filed:
Jun 6, 1995
Appl. No.:
8/480473
Inventors:
Gregg L. Semenza - Towson MD
Assignee:
The Johns Hopkins University School of Medicine - Baltimore MD
International Classification:
C12N 120, C12N 1563, C12N 500, C07H 2104
US Classification:
4352523
Abstract:
The purified and characterization of hypoxiainducible factor 1 (HIF-1) is described. HIF-1 is composed of subunits HIF-1. alpha. and HIF-1. beta. Purified HIF-1. alpha. polypeptide, its amino acid sequence and polynucleotide sequence are provided. A HIF-1. alpha. variant that dimerizes to HIF-1. beta. producing a nonfunctional HIF-1 complex is described. Methods for the prevention and treatment of hypoxia-related disorders are provided.