Inventors:
Gregg Staerkel - Houston TX
Youseph Yazdi - Austin TX
Michele F. Mitchell - Houston TX
Assignee:
Board of Regents, The University of Texas Systems - Austin TX
International Classification:
G01N 2164
Abstract:
A method for detecting tissue abnormality, particularly precancerous cervical tissue, through fluorescence spectroscopy is disclosed. In vitro fluorescence measurements over a variety of different fluorescence spectra are used to screen tissue samples. Using a principal component analysis (PCA), it is possible to discriminate between normal and dysplastic tissues with relatively low false-positive and false-negative results.