Inventors:
Greer M. Murphy - Stanford CA, US
Alan F. Schatzberg - Los Altos CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
International Classification:
C12Q 1/68, C12P 19/34, C07H 21/02, C07H 21/04
US Classification:
435 611, 435 61, 435 612, 435 613, 435 617, 435 912, 536 235, 536 2431
Abstract:
A new method is found to determine an increased risk for side effects of an SSRI treatment in a person by genotyping the person for the presence of the 102 C/C DNA sequence in the 5-HTreceptor gene. This provides for a method to improve the treatment of an SSRI responsive disorder and in particular depression.