Inventors:
William R. Jacobs - Pelham NY, US
Glenn J. Fennelly - New York NY, US
International Classification:
C12N 15/85, C12N 5/06, C12N 1/21, C12N 15/11
US Classification:
435455, 4352523, 435325, 4353201
Abstract:
Provided are mycobacteria comprising a recombinant gene operably liked to a mammalian promoter that directs expression of the recombinant gene from a mammalian cell. Also provided are mammalian cells comprising the above mycobacteria. Additionally provided are mycobacterial plasmids capable of replication in a mycobacterium. Further provided are methods of expressing a recombinant gene in a mammalian cell.