Inventors:
Glen H. Murata - Albuquerque NM, US
International Classification:
A61K 31/505, A61K 31/40, A61K 31/404, A61K 31/366, A61K 31/22, A61K 31/47, A61P 9/10, G06G 7/60
US Classification:
514275, 514423, 514419, 514460, 514510, 514311, 703 11
Abstract:
The invention provides methods for optimizing therapeutic efficacy for treating hypercholesterolemia in a subject having a cardiovascular disease (CVD), comprising (a) determining subject characteristics that affect the likelihood of reaching a goal level of low density lipoprotein (LDL); and (b) obtaining success probabilities of a variety of statin treatments for reaching said goal level of LDL using said subject characteristics and a multivariate model; and (c) administrating the optimal statin treatment with the highest success probability of step (b) to said subject thereby optimizing therapeutic efficacy for treating hypercholesterolemia in said subject.