GIHAN INDRAGITH TENNEKOON
Medical Practice in Penn Wynne, PA
License number
Pennsylvania MD055436L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Penn Wynne, PA 19096
Personal information
See more information about GIHAN INDRAGITH TENNEKOON at radaris.comName
Address
Phone
420 Bolsover Rd, Wynnewood, PA 19096
420 Bolsover, Merion, PA 19096
Professional information
Therapeutic Uses For Mesenchymal Stromal Cells
US Patent:
6673606, Jan 6, 2004
Filed:
Apr 12, 2001
Appl. No.:
09/833066
Inventors:
Gihan Tennekoon - Wynnewood PA
Andrew J. Coyle - Philadelphia PA
Judith Grinspan - Ardmore PA
Jackie S. Beesley - West Sussex, GB
Andrew J. Coyle - Philadelphia PA
Judith Grinspan - Ardmore PA
Jackie S. Beesley - West Sussex, GB
Assignee:
The Childrens Hospital of Philadelphia - Philadelphia PA
International Classification:
C12N 508
US Classification:
435372, 435325, 435366, 435368, 435377, 424 931
Abstract:
Human mesenchymal stromal cells can be induced to differentiate into oligodendrocytes and neurons, respectively. For these cell types, therefore, MSCs can be a therapeutic source, either in vitro or in vivo, in the context of treating pathologies of the central nervous system which are characterized by neuron loss, such as Parkinsons disease, Alzheimers disease and stroke, as well as head trauma, or by dysfunction in ganglioside storage or demyelinization, such as Tay-Sachs disease, G1 gangliosidosis, metachromatic leukodystrophy, and multiple sclerosis.
Therapeutic Uses For Mesenchymal Stromal Cells
US Patent:
2004020, Oct 21, 2004
Filed:
Jan 2, 2004
Appl. No.:
10/750748
Inventors:
Gihan Tennekoon - Wynnewood PA, US
Andrew Coyle - Phila. PA, US
Judith Grinspan - Ardmore PA, US
Jackie Beesley - London, GB
Andrew Coyle - Phila. PA, US
Judith Grinspan - Ardmore PA, US
Jackie Beesley - London, GB
International Classification:
A61K048/00, C12N005/08
US Classification:
424/093210, 435/368000
Abstract:
Human mesenchymal stromal cells can be induced to differentiate into oligodendrocytes and neurons, respectively. For these cell types, therefore, MSCs can be a therapeutic source, either in vitro or in vivo, in the context of treating pathologies of the central nervous system which are characterized by neuron loss, such as Parkinson's disease, Alzheimer's disease and stroke, as well as head trauma, or by dysfunction in ganglioside storage or demyelinization, such as Tay-Sachs disease, G1 gangliosidosis, metachromatic leukodystrophy, and multiple sclerosis.
Therapeutic Uses For Mesenchymal Stromal Cells
US Patent:
2007018, Aug 9, 2007
Filed:
Apr 9, 2007
Appl. No.:
11/784935
Inventors:
Gihan Tennekoon - Wynnewood PA, US
Andrew Coyle - Phila PA, US
Judith Grinspan - Ardmore PA, US
Jackie Beesley - London, GB
Andrew Coyle - Phila PA, US
Judith Grinspan - Ardmore PA, US
Jackie Beesley - London, GB
International Classification:
A61K 48/00, C12N 5/08
US Classification:
424093210, 435368000
Abstract:
Human mesenchymal stromal cells can be induced to differentiate into oligodendrocytes and neurons, respectively. For these cell types, therefore, MSCs can be a therapeutic source, either in vitro or in vivo, in the context of treating pathologies of the central nervous system which are characterized by neuron loss, such as Parkinson's disease, Alzheimer's disease and stroke, as well as head trauma, or by dysfunction in ganglioside storage or demyelinization, such as Tay-Sachs disease, G1 gangliosidosis, metachromatic leukodystrophy, and multiple sclerosis.