GERALD LOUIS DENARDO, M.D.
Osteopathic Medicine at Alhambra Blvd, Sacramento, CA
License number
California A18118
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
2
1508 Alhambra Blvd, Sacramento, CA 95816
44336 Clubhouse Dr, Davis, CA 95618
44336 Clubhouse Dr, Davis, CA 95618
Phone
(916) 734-3787
(530) 756-4157
(530) 756-4157
Personal information
See more information about GERALD LOUIS DENARDO at radaris.comName
Address
Phone
119 Segolily Ct, Lincoln, CA 95648
Lincoln, CA
44336 Clubhouse Dr, El Macero, CA 95618
119 Segolily Ct, Lincoln, CA 95648
Professional information
Gerald Louis Denardo, Sacramento CA
Specialties:
Nuclear Medicine Specialist
Address:
1508 Alhambra Blvd, Sacramento, CA 95816
Education:
University of California San Francisco, School of Medicine - Doctor of Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Nuclear Medicine Certification in Nuclear Medicine
Dr. Gerald L Denardo - MD (Doctor of Medicine)
Specialties:
Internal Medicine, Nuclear Medicine
Certifications:
Internal Medicine, 1964, Nuclear Medicine, 1972
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1508 Alhambra Blvd SUITE 3100, Sacramento 95816
UC Davis Medical Center
2315 Stockton Blvd, Sacramento 95817
1508 Alhambra Blvd SUITE 3100, Sacramento 95816
UC Davis Medical Center
2315 Stockton Blvd, Sacramento 95817
UC Davis Medical Center
2315 Stockton Blvd, Sacramento 95817
1508 Alhambra Blvd SUITE 3100, Sacramento 95816
UC Davis Medical Center
2315 Stockton Blvd, Sacramento 95817
Education:
Medical School
University of California At San Francisco
Letterman Army Medical Center
William Beaumont Army Medical Center
University of California At San Francisco
Letterman Army Medical Center
William Beaumont Army Medical Center
Anti-Muc-1 Single Chain Antibodies For Tumor Targeting
US Patent:
2003007, Apr 24, 2003
Filed:
Mar 28, 2002
Appl. No.:
10/112788
Inventors:
Sally Denardo - El Macero CA, US
Michelle Winthrop - Woodland CA, US
Gerald Denardo - El Macero CA, US
Michelle Winthrop - Woodland CA, US
Gerald Denardo - El Macero CA, US
Assignee:
University of California, Davis Technology Transfer Center
International Classification:
G01N033/574, C07K016/30
US Classification:
435/007230, 530/388260, 530/388800
Abstract:
This invention provides novel antibodies that specifically bind to the cancer antigen MUC-1. The antibodies are useful targeting moieties for specifically directing imaging agents and various thereapeutic moieties to a cancer.
Selective High Affinity Polydentate Ligands And Methods Of Making Such
US Patent:
7662785, Feb 16, 2010
Filed:
Feb 9, 2005
Appl. No.:
11/055181
Inventors:
Sally DeNardo - El Macero CA, US
Gerald DeNardo - El Macero CA, US
Rodney Balhorn - Livermore CA, US
Gerald DeNardo - El Macero CA, US
Rodney Balhorn - Livermore CA, US
Assignee:
The Regents of California - Oakland CA
Lawrence Livermore National Security, LLC - Livermore CA
Lawrence Livermore National Security, LLC - Livermore CA
International Classification:
A61K 38/08
US Classification:
514 17, 514182, 514393
Abstract:
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
Selective High-Affinity Polydentate Ligands And Methods Of Making Such
US Patent:
2011014, Jun 16, 2011
Filed:
Apr 21, 2009
Appl. No.:
12/988801
Inventors:
Sally J. Denardo - El Macero CA, US
Gerald L. Denardo - El Macero CA, US
Rodney L. Balhorn - Livermore CA, US
Gerald L. Denardo - El Macero CA, US
Rodney L. Balhorn - Livermore CA, US
International Classification:
A61K 31/655, C07C 245/08, C12Q 1/02, A61P 35/00
US Classification:
514150, 534798, 435 29
Abstract:
This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
Site-Specific Conjugation Of Ligands To Nanoparticles
US Patent:
2010017, Jul 15, 2010
Filed:
Apr 25, 2008
Appl. No.:
12/597866
Inventors:
Arutselvan Natarajan - Sacramento CA, US
Sally J. Denardo - El Macero CA, US
Gerald L. Denardo - El Macero CA, US
Cordula Gruettner - Rostock-Warnemuende, DE
Sally J. Denardo - El Macero CA, US
Gerald L. Denardo - El Macero CA, US
Cordula Gruettner - Rostock-Warnemuende, DE
Assignee:
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA - OAKLAND CA
International Classification:
C07K 14/00, C07K 2/00, C07K 16/00
US Classification:
530300, 530402, 5303911, 5303915, 977773
Abstract:
A new radioconjugate NP has been developed using recombinant antibody fragments, di-scFv-c (111 In-DOTA-di-scFv-NP) for imaging and therapy of anti MUC-1 10 expressing cancers since aberrant MUC-1 Is abundantly expressed on the majority of human epithelial cancers. Selection and engineering of anti-MUC-1 di-scFv-c (50 kDa) was generated to link NP-M (maleimide). DOTA chelate was conjugated with di-scFv-c for the radiometal chelation to trace the RINP at in vivo. This RINP preparation can provide uniquely high tumor cell binding NP for AMF driven tumor hyperthermia.
On-Demand Cleavable Linkers For Radioconjugates For Cancer Imaging And Therapy
US Patent:
2005025, Nov 17, 2005
Filed:
Nov 23, 2004
Appl. No.:
10/997759
Inventors:
Kit Lam - Davis CA, US
Pappanaicken Kumaresan - Sacramento CA, US
Sally DeNardo - Sacramento CA, US
Gerald DeNardo - Sacramento CA, US
Pappanaicken Kumaresan - Sacramento CA, US
Sally DeNardo - Sacramento CA, US
Gerald DeNardo - Sacramento CA, US
Assignee:
The Regents of the University of California Office of Technology Transfer, University of California - Oakland CA
International Classification:
A61K051/00
US Classification:
424001490
Abstract:
The present invention provides compositions comprising a biological agent, a targeting moiety, and a peptide linker attaching the biological agent to the targeting moiety, wherein the peptide linker is selectively cleaved by a protease. Efficient methods are provided for administering the compositions of the present invention for treating cancer or imaging a tumor, organ, or tissue in a subject. Kits are also provided for administering the compositions of the present invention for radiotherapy or radioimaging.
Anti-Muc-1 Single Chain Antibodies For Tumor Targeting
US Patent:
2004000, Jan 8, 2004
Filed:
May 9, 2003
Appl. No.:
10/435614
Inventors:
Sally Denardo - El Macero CA, US
Michelle Winthrop - Woodland CA, US
Gerald Denardo - El Macero CA, US
Michelle Winthrop - Woodland CA, US
Gerald Denardo - El Macero CA, US
Assignee:
The Regents of the University of California
International Classification:
G01N033/574, C07K016/30
US Classification:
435/007230, 530/388250
Abstract:
This invention provides novel antibodies that specifically bind to the cancer antigen MUC-1. The antibodies are useful targeting moieties for specifically directing imaging agents and various therapeutic moieties to a cancer.