GEORGE NORMAN ABRAHAM, MD
Osteopathic Medicine at Elmwood Ave, Rochester, NY
License number
New York 126366
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
600 Elmwood Ave, Rochester, NY 14642
Phone
(585) 275-7950
(585) 275-4911
(585) 276-2743 (Fax)
(585) 275-4911
(585) 276-2743 (Fax)
Professional information
Professor Of Medicine, Microioblogy And Immunology At University Of Rochester Medical Center
Position:
Professor of Medicine, Microioblogy and Immunology at University of Rochester Medical Center
Location:
Rochester, New York Area
Industry:
Research
Work:
University of Rochester Medical Center
-
Professor of Medicine, Microioblogy and Immunology
Cancer Therapy Utilizing Ex Vivo Gene Transduction
US Patent:
6110458, Aug 29, 2000
Filed:
May 25, 1995
Appl. No.:
8/450011
Inventors:
Scott M. Freeman - New Orleans LA
George N. Abraham - Rochester NY
Craig S. McCune - Huson NY
Frederick L. Moolten - West Newton MA
David Koeplin - Los Angeles CA
George N. Abraham - Rochester NY
Craig S. McCune - Huson NY
Frederick L. Moolten - West Newton MA
David Koeplin - Los Angeles CA
Assignee:
University of Rochester - Rochester NY
International Classification:
A61K 4800, C12N 1500, C12N 1563, C12N 500
US Classification:
424 9321
Abstract:
A method is provided for eliminating cancer cells from a population of cells containing cancer cells and noncancerous cells in vitro or in vivo comprising: (a) providing a mixture of noncancerous cells and cancer cells; (b) contacting the cancer cells with transgenic cancer cells comprising a foreign gene that renders the transgenic cancer cells susceptible to a therapeutic agent; and (c) contacting the transgenic cancer cells with an amount of said therapeutic agent effective to kill both the transgenic cancer cells and the cancer cells.
Cancer Therapy Utilizing Malignant Cells Expressing Hsv-Tk
US Patent:
5601818, Feb 11, 1997
Filed:
Dec 8, 1994
Appl. No.:
8/351891
Inventors:
Scott M. Freeman - New Orleans LA
George N. Abraham - Rochester NY
Craig S. McCune - Huson NY
Frederick L. Moolten - West Newton MA
David Koeplin - Los Angeles CA
George N. Abraham - Rochester NY
Craig S. McCune - Huson NY
Frederick L. Moolten - West Newton MA
David Koeplin - Los Angeles CA
Assignee:
University of Rochester - Rochester NY
International Classification:
A61K 4800, C12N 1500
US Classification:
424 9321
Abstract:
A method is provided for eliminating cancer cells from a population of cells containing cancer cells and noncancerous cells in vitro or in vivo comprising: (a) providing a mixture of noncancerous cells and cancer cells; (b) contacting the cancer cells with transgenic cancer cells comprising a foreign gene such as the herpes virus thymidine kinase gene that renders the transgenic cancer cells susceptible to a therapeutic agent; and (c) contacting the transgenic cancer cells with an amount of said therapeutic agent effective to kill both the transgenic cancer cells and the cancer cells.