GEORGE LUTHER MUTTER, MD
Medical Practice in Boston, MA
License number
Massachusetts 59159
Category
Medical Practice
Type
Anatomic Pathology
Address
Address
75 Brigham And Womens Hospital Department Of Pathology, Boston, MA 02115
Phone
(617) 732-7536
Personal information
See more information about GEORGE LUTHER MUTTER at radaris.comName
Address
Phone
230 Middlesex Rd, Chestnut Hill, MA 02467
230 Middlesex Rd, Chestnut Hill, MA 02467
25 Eliot St, Jamaica Plain, MA 02130
230 Middlesex, Brookline, MA 02467
Professional information
Prognostic Classification Of Breast Cancer Through Determination Of Nucleic Acid Sequence Expression
US Patent:
6703204, Mar 9, 2004
Filed:
Jul 27, 2001
Appl. No.:
09/917254
Inventors:
George L. Mutter - Chestnut Hill MA
Jan P. A. Baak - Tananger, NO
Jan P. A. Baak - Tananger, NO
Assignee:
The Brigham Womens Hospital, Inc. - Boston MA
International Classification:
C12Q 168
US Classification:
435 6, 435 912, 536 235, 536 2431, 536 2433
Abstract:
The invention provides particular sets of genes that are expressed differentially in tumors characterized as high MAI or low MAI tumors. These sets of genes can be used to discriminate between high and low MAI tumors. Diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression are also provided.
George Luther Mutter, Boston MA
Specialties:
Pathologist
Address:
75 Francis St, Boston, MA 02115
Education:
Harvard Medical School - Doctor of Medicine
Board certifications:
American Board of Pathology Certification in Anatomic Pathology (Pathology)
Dr. George L Mutter, Boston MA - MD (Doctor of Medicine)
Specialties:
Anatomic Pathology
Address:
75 Francis St, Boston 02115
(617) 732-7536 (Phone)
(617) 732-7536 (Phone)
Certifications:
Anatomic Pathology, 1986
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
75 Francis St, Boston 02115
Brigham and Women's Hospital
75 Francis St, Boston 02115
Brigham and Women's Hospital
75 Francis St, Boston 02115
Education:
Medical School
Harvard Medical School
Graduated: 1982
Colum Presby Med Center
Graduated: 1986
Graduated: 1988
Harvard Medical School
Graduated: 1982
Colum Presby Med Center
Graduated: 1986
Graduated: 1988
Prognostic Classification Of Endometrial Cancer
US Patent:
6773883, Aug 10, 2004
Filed:
Jul 31, 2001
Appl. No.:
09/919497
Inventors:
George L. Mutter - Chestnut Hill MA
Assignee:
The Brigham Womens Hospital, Inc. - Boston MA
International Classification:
C12Q 168
US Classification:
435 6, 436504, 436 64
Abstract:
The invention provided sets of genes that are expressed differentially in normal and malignant endometrium. These sets of genes can be used to discriminate between normal and malignant endometrial tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.
Method And Display For Multivariate Classification
US Patent:
6868342, Mar 15, 2005
Filed:
Oct 12, 2001
Appl. No.:
09/977054
Inventors:
George L. Mutter - Chestnut Hill MA, US
Assignee:
The Brigham & Women's Hospital, Inc. - Boston MA
International Classification:
G06F019/00, B06K009/52
US Classification:
702 21, 706 20, 382228
Abstract:
The present invention represents a new approach to data analysis for multivariate classification, particularly as used in medical diagnostics. The invention is in part an intuitive decision making tool for rapid classification of “objects” (e. g. , cell, tissue or tumor samples) from evaluation of many simultaneous “variables” (e. g. , quantitative gene expression profiles). The data analysis methods of the invention provide the end user with a simplified and robust output for diagnostic classification of objects based on identifying and evaluating multiple variables of predetermined diagnostic relevance. The raw data generated by analysis of the variables is transformed by application or appropriate algorithms to scaleless rank differentials between the variables. The rank orders of variables are used to classify tissues based on readily observable user interfaces, such as a graphical (e. g. , visual) user interface or an auditory user interface.
Chemoprevention Of Endometrial Cancer
US Patent:
7858332, Dec 28, 2010
Filed:
Jan 22, 2007
Appl. No.:
11/655895
Inventors:
George Mutter - Chestnut Hill MA, US
Akila Viswanathan - Cambridge MA, US
Anne Ørbo - Tromso, NO
Akila Viswanathan - Cambridge MA, US
Anne Ørbo - Tromso, NO
Assignee:
The Brigham and Women's Hospital, Inc. - Boston MA
University of Tromsø - Tromsø
University of Tromsø - Tromsø
International Classification:
G01N 33/53
US Classification:
435 723, 4241981
Abstract:
The present invention is directed to intrauterine devices that release progestins or an inflammatory cytokine after placement. These devices can be used to reduce the risk of a woman developing endometrial cancer. The invention is also directed to therapeutic methods in which a sample of uterine cells obtained from a woman is assayed to determine the extent to which PTEN null clones (latent endometrial precancers) are present. In cases where the number of such null clones is high, the woman is administered an intrauterine device that releases either a progestin or an inflammatory cytokine.
Diagnosis Of Endometrial Precancers
US Patent:
2002006, May 23, 2002
Filed:
May 31, 2001
Appl. No.:
09/871579
Inventors:
George Mutter - Chestnut Hill MA, US
Charis Eng - Columbus OH, US
Charis Eng - Columbus OH, US
International Classification:
C12Q001/68, G01N033/53, G01N033/567, G01N033/574, C07H021/02, C07H021/04, C12P019/34, C07K001/00, C07K014/00, C07K017/00, C07K016/00, C12P021/08
US Classification:
435/007200, 435/007100, 435/007210, 435/007230, 530/387100, 530/388100, 530/388800, 530/391300, 530/388240, 435/006000, 435/091200, 536/023100, 536/024300, 530/350000
Abstract:
The invention disclosed herein describes novel methods for diagnosing endometrial precancers by measuring PTEN expression and offers an immunohistochemical biomarker for premalignant disease.