GEORGE J WEINER, MD
Osteopathic Medicine at Hawkins Dr, Iowa City, IA

License number
Iowa 27176
Category
Osteopathic Medicine
Type
Hematology & Oncology
Address
Address
200 Hawkins Dr, Iowa City, IA 52242
Phone
(319) 353-8620
(319) 353-8988 (Fax)

Organization information

See more information about GEORGE J WEINER at bizstanding.com

University Of Iowa Hosps CLNCS - George J Weiner MD

200 Hawkins Dr #C32GH, Iowa City, IA 52242

Categories:
Family & General Practice Physicians & Surgeons, Hematology Physicians & Surgeons, Internal Medicine Physicians & Surgeons, ...
Phone:
(319) 353-8504 (Phone)

Professional information

George Weiner Photo 1

Professor And Cancer Center Director, University Of Iowa

Position:
Professor at University of Iowa
Location:
Iowa City, Iowa Area
Industry:
Hospital & Health Care
Work:
University of Iowa since 1989 - Professor
Education:
The Ohio State University College of Medicine 1978 - 1981
MD
Johns Hopkins University 1974 - 1978
BA, Natural Science


George Weiner Photo 2

Prostate Cell Surface Antigen-Specific Antibodies

US Patent:
6512096, Jan 28, 2003
Filed:
Jan 9, 2001
Appl. No.:
09/757336
Inventors:
George J. Weiner - Iowa City IA
Oskar W. Rokhlin - Coralville IA
Michael B. Cohen - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A61K 34395
US Classification:
53038885, 5303873, 5303881, 5303917
Abstract:
Disclosed is an antibody that binds to a protein found on normal and cancerous prostate cells, but not found on nonprostate cells and a hybridoma that produces the antibody to the prostate-specific protein. Also disclosed are antibodies conjugated to labels or cytotoxic moieties.


George Weiner Photo 3

Prostate Cell Surface Antigen-Specific Antibodies

US Patent:
6207805, Mar 27, 2001
Filed:
Jun 25, 1998
Appl. No.:
9/104717
Inventors:
George J. Weiner - Iowa City IA
Oskar W. Rokhlin - Coralville IA
Michael B. Cohen - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A61K34/395
US Classification:
53038885
Abstract:
Disclosed is an antibody that binds to a protein found on normal and cancerous prostate cells, but not found on nonprostate cells and a hybridoma that produces the antibody to the prostate-specific protein. Also disclosed are antibodies conjugated to labels or cytotoxic moieties.


George Weiner Photo 4

Methods Of Identifying Metastatic Potential In Cancer

US Patent:
2006011, Jun 1, 2006
Filed:
Oct 11, 2005
Appl. No.:
11/248016
Inventors:
Doina Racila - North Liberty IA, US
Emilian Racila - North Liberty IA, US
George Weiner - Iowa City IA, US
International Classification:
G01N 33/53
US Classification:
435006000
Abstract:
The present invention encompasses methods for predicting metastasis in cancer by assessing the structure of the complement protein C1qA. The methods may encompass examining either protein or nucleic acids, and may further include making treatment decisions based on the predictive methods.


George Weiner Photo 5

Methods And Products For Stimulating The Immune System Using Immunotherapeutic Oligonucleotides And Cytokines

US Patent:
2005019, Sep 8, 2005
Filed:
Apr 19, 2005
Appl. No.:
11/110189
Inventors:
Arthur Krieg - Iowa City IA, US
George Weiner - Iowa City IA, US
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A61K048/00
US Classification:
514044000
Abstract:
The present invention relates to synergistic combinations of immunostimulatory CpG oligonucleotides and immunopotentiating cytokines. In particular, the invention relates to methods of stimulating an immune response using the synergistic combination of compounds and products related thereto.


George Weiner Photo 6

Methods And Products For Stimulating The Immune System Using Immunotherapeutic Oligonucleotides And Cytokines

US Patent:
6218371, Apr 17, 2001
Filed:
Apr 2, 1999
Appl. No.:
9/286098
Inventors:
Arthur M. Krieg - Iowa City IA
George Weiner - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A01N 4304, A01N 3718, A61K 3900, C12Q 168, C07H 2102
US Classification:
514 44
Abstract:
The present invention relates to synergistic combinations of immunostimulatory CpG oligonucleotides and immunopotentiating cytokines. In particular, the invention relates to methods of stimulating an immune response using the synergistic combination of compounds and products related thereto.


George Weiner Photo 7

Methods Of Treating Cancer Using Immunostimulatory Oligonucleotides

US Patent:
2004008, May 6, 2004
Filed:
Nov 21, 2003
Appl. No.:
10/719493
Inventors:
Arthur Krieg - Wellesley MA, US
George Weiner - Iowa City IA, US
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
A61K048/00, C12Q001/68, C07H021/04
US Classification:
514/044000, 435/006000, 536/023100
Abstract:
Nucleic acid sequences containing unmethylated CpG dinucleotides that modulate an immune response including stimulating a Th1 pattern of immune activation, cytokine production, NK lytic activity, and B cell proliferation are disclosed. The sequences are also useful as a synthetic adjuvant.


George Weiner Photo 8

Bispecific Antibody Effective To Treat B-Cell Lymphoma And Cell Line

US Patent:
6129914, Oct 10, 2000
Filed:
Mar 1, 1995
Appl. No.:
8/397411
Inventors:
George Weiner - Iowa City IA
Roger Gingrich - Iowa City IA
Brian K. Link - Carlville IA
J. Yun Tso - Menlo Park CA
Assignee:
Protein Design Labs, Inc. - Fremont CA
International Classification:
A61K 39395, C12P 2104, C12P 2108, C07K 1600
US Classification:
4241331
Abstract:
The invention provides bispecific antibodies with selective cytotoxicity against malignant B-cells. The bispecific antibodies bind to an effector cell antigen and to a 28/32 kDa heterodimeric protein on the surface of malignant B-cells. The invention also includes the monospecific components of the bispecific antibodies, humanized versions thereof, and humanized bispecific antibodies. The invention further provides therapeutic and diagnostic methods employing these antibodies.


George Weiner Photo 9

Humanized Antibodies Against Cd3

US Patent:
2004005, Mar 18, 2004
Filed:
May 9, 2003
Appl. No.:
10/435299
Inventors:
George Weiner - Iowa City IA, US
Roger Gingrich - Iowa City IA, US
Brian Link - Carlville IA, US
J. Tso - Menlo Park CA, US
International Classification:
A61K039/395, C12N005/06, C07K016/30
US Classification:
424/133100, 530/388800, 435/327000
Abstract:
The invention provides bispecific antibodies with selective cytotoxicity against malignant B-cells. The bispecific antibodies bind to an effector cell antigen and to a 28/32 kDa heterodimeric protein on the surface of malignant B-cells. The invention also includes the monospecific components of the bispecific antibodies, humanized versions thereof, and humanized bispecific antibodies. The invention further provides therapeutic and diagnostic methods employing these antibodies.


George Weiner Photo 10

Compositions Comprising Immunostimulatory Oligonucleotides And Uses Thereof To Enhance Fc Receptor-Mediated Immunotherapies

US Patent:
2003007, Apr 17, 2003
Filed:
Jul 30, 2002
Appl. No.:
10/209070
Inventors:
Jan van de Winkel - Zeist, NL
George Weiner - Iowa City IA, US
International Classification:
A61K039/395, A61K048/00, A61K039/40
US Classification:
424/178100, 514/044000
Abstract:
Compositions comprising immunostimulatory oligonucleotides (CpG ODN) and FcR-directed immunotherapeutics are disclosed. Also disclosed are methods of using the compositions to enhance FcR-mediated antigen presentation, ADCC, and other FcR-mediated immune responses.