Inventors:
George A. Beller - Charlottesville VA, US
David K. Glover - Charlottesville VA, US
Alexander L. Klibanov - Charlottesville VA, US
Craig H. Meyer - Charlottesville VA, US
Dayuan Li - Charlottesville VA, US
Amit Patel - Chicago IL, US
Christopher M. Kramer - Charlottesville VA, US
Assignee:
University of Virginia Patent Foundation - Charlottesville VA
International Classification:
A61K 49/16, A61K 51/10, A61K 51/12, A61K 39/395, A61B 5/055, C07K 16/00
US Classification:
424 137, 424 149, 424 153, 424 9321, 4241431
Abstract:
The present invention provides multiple modalities for detecting LOX-1. More particularly, an imaging composition is provided that allows for the in vivo imaging of atherosclerotic plaque.