GEOFFREY GRAHAM WILSON
Pilots in Hamilton, MA
License number
Massachusetts A2305706
Issued Date
May 2016
Expiration Date
May 2018
Category
Airmen
Type
Authorized Aircraft Instructor
Address
Address
PO Box 233, Hamilton, MA 01936
Professional information
Novel Modular Type Ii Restriction Endonuclease, Cspci, And The Use Of Modular Endonucleases For Generating Endonucleases With New Specificities
US Patent:
2007016, Jul 19, 2007
Filed:
Mar 23, 2005
Appl. No.:
10/593790
Inventors:
Richard Morgan - Middleton MA, US
Geoffrey Wilson - South Hamilton MA, US
Keith Lunnen - Essex MA, US
Daniel Heiter - Groveland MA, US
Jack Benner - South Hamilton MA, US
Celine Nkenfou - Yaounde, CM
Stephen Picone - Beverly MA, US
Geoffrey Wilson - South Hamilton MA, US
Keith Lunnen - Essex MA, US
Daniel Heiter - Groveland MA, US
Jack Benner - South Hamilton MA, US
Celine Nkenfou - Yaounde, CM
Stephen Picone - Beverly MA, US
Assignee:
New England Biolabs, Inc. - Ipswich MA
International Classification:
C12Q 1/68, C07H 21/04, C12P 21/06, C12N 9/22, C12N 15/74, C12N 1/21
US Classification:
435006000, 435069100, 435199000, 435252330, 435488000, 536023200
Abstract:
A novel restriction endonuclease and methods of making the same are obtainable from either species 2144 (NEB#1398) or the recombinant stain (NEB#1554) which cleaves at nt sequence 5′-CAANNNNNGTGG-3′ (SEQ ID NO:14) in double-stranded DNA molecules. The novel restriction endonuclease is a modular protein in which the specificity moiety is an independent module from the restriction-modification module.
Detection And Quantification Of Hydroxymethylated Nucleotides In A Polynucleotide Preparation
US Patent:
2012015, Jun 21, 2012
Filed:
Aug 25, 2010
Appl. No.:
13/392286
Inventors:
Jurate Bitinaite - Rowley MA, US
Romualdas Vaisvila - Ipswich MA, US
Sriharsa Pradhan - Wenham MA, US
Yu Zheng - Topsfield MA, US
Richard J. Roberts - Wenham MA, US
Christopher Noren - Boxford MA, US
Elisabeth A. Raleigh - Somerville MA, US
Geoffrey Wilson - South Hamilton MA, US
Romualdas Vaisvila - Ipswich MA, US
Sriharsa Pradhan - Wenham MA, US
Yu Zheng - Topsfield MA, US
Richard J. Roberts - Wenham MA, US
Christopher Noren - Boxford MA, US
Elisabeth A. Raleigh - Somerville MA, US
Geoffrey Wilson - South Hamilton MA, US
Assignee:
NEW ENGLAND BIOLABS, INC. - Ipswich MA
International Classification:
C12Q 1/68
US Classification:
435 611
Abstract:
Methods and compositions are described for detecting hydroxymethylated nucleotides (hmNs) in a polynucleotide preparation with a view to mapping the location of hmNs in a genome, quantifying the occurrence of hmNs at selected loci and correlating the occurrence of hmNs with gene expression and phenotypic traits. Embodiments describe the use of modifying enzymes together with site-specific endonucleases to detect the hmNs.
Method For Cloning And Expression Of Acc65I Restriction Endonuclease And Acc65I Methylase In
US Patent:
7795408, Sep 14, 2010
Filed:
Jun 14, 2007
Appl. No.:
11/818298
Inventors:
Keith Lunnen - Essex MA, US
John Greci - Manchester MA, US
Geoffrey Wilson - South Hamilton MA, US
John Greci - Manchester MA, US
Geoffrey Wilson - South Hamilton MA, US
Assignee:
New England Biolabs, Inc. - Ipswich MA
International Classification:
C07H 21/02, C07H 21/04, C12P 21/06, C12N 1/20, C12N 15/74
US Classification:
536 231, 435471, 435 691, 4352523
Abstract:
An isolated DNA is provided which encodes a protein that is capable of binding to 5′GGTACC-3′, the isolated DNA being capable of hybridizing to SEQ ID NO:3 under stringent hybridization conditions. The isolated DNA may be alternatively characterized as coding for a protein having an amino acid sequence comprising SEQ ID NO:5 or by an amino acid sequence with an expectation value of less than E=ein a BLAST search using SEQ ID NO:5. Vectors containing the isolated DNA and host cells expressing the vectors as well as a method for making recombinant Acc65I having the above properties are also provided.