GAYLE D HEFFERNAN
Pharmacy in Middlesex, NJ

6719733, Apr 13, 2004

Nov 8, 1996

08/746304

Gayle Heffernan - Middlesex NJ
Allen Welsher - East Brunswick NJ

Bracco International B.V. - Amsterdam

A61M 532

604199, 53122, 53428, 264232, 604232, 141 11

A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the barrel and a piston capable of sliding in the barrel and sealing the open end of the barrel opposite the nozzle, comprising the steps of: (a) providing at least one component of said syringe which is molded under conditions which are substantially free of pyrogens and viable and non-viable articulates; and (b) filling and assembling said syringe.

2005025, Nov 10, 2005

May 10, 2004

10/842610

George Armstrong - Franklin Park NJ, US
Ernest Balestracci - Iselin NJ, US
Barry DeDominicis - Holland PA, US
Gayle Heffernan - Middlesex NJ, US
Charles Quirco - Warren NJ, US

A61M005/315

604218000, 604181000

A prefilled syringe assembly that includes a syringe barrel of cylindrical configuration having an inner surface that defines a cylindrical chamber, a shoulder portion connected to the cylindrical chamber, a neck portion connected to the shoulder portion and a tapered tip that terminates at the distal end. The tapered tip extends a first distance along the neck portion toward the distal end and having a shaft and a bore therethrough. The syringe barrel further includes a luer collar that terminates at the distal end and extends a second distance along the longitudinal axis from the neck portion toward the distal end such that the second distance is about equal to the first distance. The prefilled syringe assembly also includes a piston that is received through the proximal end and is positioned within the syringe barrel. The prefilled syringe assembly provides an elastomeric plug that is disposed at the distal end which protects the tapered tip from external forces and microscopic crazing during sterilization.

5620425, Apr 15, 1997

Nov 3, 1993

8/147353

Gayle Heffernan - Middlesex NJ
Allen Welsher - East Brunswick NJ

Bracco International B.V. - Amsterdam

A61M 100

604281

A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent, wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the barrel and a piston capable of sliding in the barrel and sealing the open end of the barrel opposite the nozzle, comprising the steps of (a) providing at least one component of said syringe which is molded under conditions which are substantially free of pyrogens and viable and non-viable particulates; and (b) filling and assembling said syringe.

2011001, Jan 27, 2011

Jul 26, 2010

12/843703

Gayle Heffernan - Middlesex NJ, US
Allen Welsher - East Brunswick NJ, US

BRACCO INTERNATIONAL B.V. - Amsterdam

B65B 3/04, B28B 11/00

141 2, 264232, 2642971

A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the barrel and a piston capable of sliding in the barrel and sealing the open end of the barrel opposite the nozzle, comprising the steps of:

2009006, Mar 5, 2009

Oct 28, 2008

12/259749

Gayle Heffernan - Middlesex NJ, US
Allen Welsher - East Brunswick NJ, US

A61M 5/30, B29C 45/00

604199, 264242

A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the barrel and a piston capable of sliding in the barrel and sealing the open end of the barrel opposite the nozzle, comprising the steps of:

2005001, Jan 27, 2005

Aug 19, 2004

10/921678

Gayle Heffernan - Middlesex NJ, US
Allen Welsher - East Brunswick NJ, US

B44C001/00

264603000, 428028000

A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the barrel and a piston capable of sliding in the barrel and sealing the open end of the barrel opposite the nozzle, comprising the steps of: (a) providing at least one component of said syringe which is molded under conditions which are substantially free of pyrogens and viable and non-viable particulates; and (b) filling and assembling said syringe.

7509784, Mar 31, 2009

Jan 27, 2003

10/351703

Gayle Heffernan - Middlesex NJ, US
Allen Welsher - East Brunswick NJ, US

Bracco International B.V. - Amsterdam

B65B 55/00

53122, 141 11

A novel method for the preparation of a pre-filled plastic syringe, and preferably the preparation of a plastic syringe pre-filled with a diagnostic contrast agent wherein said syringe comprises as components a barrel, a tip seal capable of sealing the nozzle of the barrel and a piston capable of sliding in the barrel and sealing the open end of the barrel opposite the nozzle, comprising the steps of:(a) providing at least one component of said syringe which is molded under conditions which are substantially free of pyrogens and viable and non-viable particulates; and(b) filling and assembling said syringe.