GASTON DE LOS REYES
Engineering in Somerville, MA
License number
Massachusetts 46318
Issued Date
Jul 12, 2005
Expiration Date
Jun 30, 2018
Type
Chemical Engineer
Address
Address
Somerville, MA 02144
Professional information
Porous Interpenetrating Polymer Network
US Patent:
8298657, Oct 30, 2012
Filed:
May 5, 2011
Appl. No.:
13/101194
Inventors:
Alex Garfield Bonner - Lexington MA, US
Lawrence Udell - Needham MA, US
David Wells Andrews - Amesbury MA, US
Gaston De Los Reyes - Somerville MA, US
Lawrence Udell - Needham MA, US
David Wells Andrews - Amesbury MA, US
Gaston De Los Reyes - Somerville MA, US
International Classification:
B32B 3/00, B29C 44/12, B05B 3/00, D21F 11/00
US Classification:
4283142, 264 28, 264 453, 162141, 162146
Abstract:
A functional, porous, interpenetrating polymer network (IPN) includes a first polymer network in the form of a porogenic support fabric (PSF) composed of linear polymers in the form of a pre-formed network comprising a fibrous composite and a second polymer network synthesized, gelated, and/or cross-linked in the presence of the first polymer network to form a system of polymers which have their respective chains held in place by means of permanent physical entanglements produced by the interweaving of the component polymer networks. The IPN is modified by dissolving and dispersing a portion of the PSF fibers, the dispersible fiber network (DFN) to form a pre-designed interconnected pore structure. The resultant porous, supported, second polymer network has convective flow, diffusive flow, and high capacity, and may include functional capture chemistries to provide an adsorptive media for chromatography and filtration of various compounds including biomolecules.
Tangential Flow Filtration System
US Patent:
8231787, Jul 31, 2012
Filed:
May 5, 2009
Appl. No.:
12/435481
Inventors:
Leon Mir - Brookline MA, US
Gaston de los Reyes - Somerville MA, US
Gaston de los Reyes - Somerville MA, US
Assignee:
SPF Innovations, LLC - Sommerville MA
International Classification:
B01D 61/00, B01D 63/00, B01D 35/00, B01D 21/30
US Classification:
210650, 210 85, 210 90, 210134, 21032165
Abstract:
A system, method and device are disclosed for bio-processing a feed stream providing a constant output by operating a continuous single-pass tangential-flow process. Embodiments are operated without large circulation pumps. Other embodiments use components which can be disposed after a single use. The system, method and device can also be used to provide constant output diafiltration.
Method And Apparatus For The Filtration Of Biological Samples
US Patent:
8231788, Jul 31, 2012
Filed:
Feb 15, 2009
Appl. No.:
12/371611
Inventors:
Leon Mir - Brookline MA, US
Gaston de los Reyes - Somerville MA, US
Gaston de los Reyes - Somerville MA, US
Assignee:
SPF Innovations, LLC - Sommerville MA
International Classification:
B01D 61/00, B01D 63/00, B01D 35/00
US Classification:
210651, 2102572, 21032174, 210 90, 21032175, 422535
Abstract:
A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to: channel void volume; volume of a sample feed reservoir; and volume of the feed sample. In another embodiment, the separation module includes two reservoirs and a hydrophobic vent. The single-pass process provides high conversion while operating with relatively low pressure sources.
Method And Apparatus For The Filtration Of Biological Solutions
US Patent:
7682511, Mar 23, 2010
Filed:
May 3, 2008
Appl. No.:
12/114751
Inventors:
Gaston de los Reyes - Somerville MA, US
Leon Mir - Newton MA, US
Leon Mir - Newton MA, US
Assignee:
SPF Innovations, LLC - Watertown MA
International Classification:
B01D 61/00
US Classification:
210637, 21032165, 21032172, 21032174, 21032176, 210650
Abstract:
A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.
Method And Apparatus For The Filtration Of Biological Samples
US Patent:
7510654, Mar 31, 2009
Filed:
Dec 22, 2006
Appl. No.:
11/615031
Inventors:
Leon Mir - Newton MA, US
Gaston de los Reyes - Somerville MA, US
Gaston de los Reyes - Somerville MA, US
Assignee:
SPF Innovations, LLC - Watertown MA
International Classification:
B01D 63/00, B01L 11/00, B01D 61/00
US Classification:
2103216, 21032174, 210474, 2103218, 210232, 210261, 422101
Abstract:
A separation module and method are disclosed for processing a liquid sample and providing high conversion by operating a single-pass tangential-flow process without a recirculation loop. In one embodiment, the separation module includes three reservoirs and has at least one long, thin channel with a large ratio of channel membrane area to: channel void volume; volume of a sample feed reservoir; and volume of the feed sample. In another embodiment, the separation module includes two reservoirs and a hydrophobic vent. The single-pass process provides high conversion while operating with relatively low pressure sources.
Method And Apparatus For The Filtration Of Biological Solutions
US Patent:
7384549, Jun 10, 2008
Filed:
Dec 22, 2006
Appl. No.:
11/615028
Inventors:
Gaston de los Reyes - Somerville MA, US
Leon Mir - Newton MA, US
Leon Mir - Newton MA, US
Assignee:
SPF Innovations, LLC - Watertown MA
International Classification:
B01D 63/00
US Classification:
21032172, 21032175, 21032178
Abstract:
A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.
Method And Apparatus For The Filtration Of Biological Solutions
US Patent:
2012016, Jul 5, 2012
Filed:
Mar 9, 2012
Appl. No.:
13/416487
Inventors:
Gaston de los Reyes - Somerville MA, US
Leon Mir - Brookline MA, US
Leon Mir - Brookline MA, US
Assignee:
SPF INNOVATIONS, LLC - Belmont MA
International Classification:
B01D 61/28
US Classification:
21032171, 21032172, 2103218, 21032178
Abstract:
A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.
Method And Apparatus For The Filtration Of Biological Solutions
US Patent:
7967987, Jun 28, 2011
Filed:
Jan 11, 2010
Appl. No.:
12/685192
Inventors:
Gaston de los Reyes - Somerville MA, US
Leon Mir - Brookline MA, US
Leon Mir - Brookline MA, US
Assignee:
SPF Innovations, LLC - Somerville MA
International Classification:
B01D 61/22
US Classification:
210637, 95 45, 96 9, 2101951, 21032165, 21032172, 210650, 210805
Abstract:
A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.
Method And Apparatus For The Filtration Of Biological Solutions
US Patent:
8157999, Apr 17, 2012
Filed:
May 15, 2011
Appl. No.:
13/107917
Inventors:
Gaston de los Reyes - Somerville MA, US
Leon Mir - Brookline MA, US
Leon Mir - Brookline MA, US
Assignee:
SPF Innovations, LLC - Somerville MA
International Classification:
B01D 63/06
US Classification:
21032172, 96 8, 96 9, 21032175, 21032179, 2103218, 21032181
Abstract:
A system, method and device are disclosed for bio-processing a feed stream and providing a constant output by operating a continuous single-pass tangential-flow process. The single-pass process provides high conversion concentration while operating at relatively low feed flow rates, and the process can also be used to provide constant output diafiltration.