Inventors:
Gary Horwith - Gaithersburg MD, US
Ali Fattom - Rockville MD, US
International Classification:
A61K 39/40, A61K 35/54
Abstract:
The present invention provides a method of preventing or treating bacteremia caused by comprising administering a monoclonal or polyclonal antibody composition comprising antibodies specific for one or more antigens. In one specific embodiment, the composition is a hyperimmune specific IGIV composition. In another specific embodiment, the composition comprise antibodies to a capsular polysaccharide antigen, such as the Type 5 and/or Type 8 antigens. In another embodiment, the composition comprises monoclonal antibodies to a capsular polysaccharide antigen. This method provides an effective tool for preventing or treating bacteremia, and can be used alone or in combination with other therapies.