GARY J WHITE
Broker in Marlboro, MA
License number
Massachusetts 9043082
Issued Date
Jan 25, 2002
Expiration Date
Jan 16, 2017
Type
Broker
Address
Address
Marlboro, MA 01752
Professional information
Compositions And Methods For Inhibiting Interleukin Pathways
US Patent:
2011005, Mar 3, 2011
Filed:
Mar 25, 2010
Appl. No.:
12/731772
Inventors:
Abraham Scaria - Framingham MA, US
Gary White - Marlborough MA, US
Gary White - Marlborough MA, US
Assignee:
GENZYME CORPORATION - Cambridge MA
International Classification:
A61K 39/395, C07K 16/28, C07H 21/00, A61K 35/12, A61K 31/7088, A61K 35/76, A61P 29/00, A61P 19/02, A61P 3/10, A61P 17/06, A61P 11/06, C12N 7/01, C12N 5/10, C12N 15/79, C12N 15/861
US Classification:
4241341, 5303873, 536 234, 424 937, 514 44 R, 424 932, 4352351, 435325, 435455, 435456
Abstract:
Fusion proteins including an IL-17 receptor with a multimerization domain, or an IL-23 receptor and a multimerization domain, and recombinant viral vectors encoding such fusions, are described. The fusion proteins and vectors encoding such fusions, alone or in combination, can be used in methods for modulating the IL-17 and IL-23 signaling pathways and for treating or preventing diseases mediated by interleukin-17 and interleukin-23, such as immune-related and inflammatory diseases.