MR. GARY GENE SMITH, MSW
Social Work at Pauline Blvd, Ann Arbor, MI
License number
Michigan 6801088994
Category
Social Work
Type
Clinical
Address
Address
1945 Pauline Blvd SUITE 14, Ann Arbor, MI 48103
Phone
(734) 764-3471
(734) 646-3581
(734) 646-3581
Professional information
Gary G Smith, Ann Arbor MI - MSW (Master of Social Work)
Specialties:
Social Work, Clinical Social Work
Address:
1945 Pauline Blvd STE 14, Ann Arbor 48103
(734) 764-3471 (Phone)
(734) 764-3471 (Phone)
Languages:
English
Microfluidic Cell Culture Device And Method For Using Same
US Patent:
2010024, Sep 30, 2010
Filed:
Oct 17, 2006
Appl. No.:
11/582259
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Lourdes Marcella Cabrera - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Yun Seok Heo - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Lourdes Marcella Cabrera - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Yun Seok Heo - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
International Classification:
B01L 3/00
US Classification:
422100
Abstract:
Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.
Methods And Compositions For Growth Of Embryonic Stem Cells
US Patent:
2010006, Mar 18, 2010
Filed:
Mar 7, 2008
Appl. No.:
12/530126
Inventors:
Gary D. Smith - Ann Arbor MI, US
Joerg Lahann - Ann Arbor MI, US
Jun Ding - Ann Arbor MI, US
Himabindu Nandivada - Ann Arbor MI, US
Joerg Lahann - Ann Arbor MI, US
Jun Ding - Ann Arbor MI, US
Himabindu Nandivada - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
C12N 5/02
US Classification:
435377, 435404, 435395
Abstract:
The present invention provides methods and compositions for establishing and maintaining growth of undifferentiated stem cells. In particular, the present invention provides synthetic growth matrices for stem cells, wherein said cells are capable of going through multiple passages while remaining in an undifferentiated state.
Integrated Microfluidic Control Employing Programmable Tactile Actuators
US Patent:
8313941, Nov 20, 2012
Filed:
May 20, 2010
Appl. No.:
12/783650
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Wei Gu - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Yunseok Heo - Ann Arbor MI, US
Brenda S. Cho - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Wei Gu - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Yunseok Heo - Ann Arbor MI, US
Brenda S. Cho - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Assignee:
The Regents of The University of Michigan - Ann Arbor MI
International Classification:
C12M 1/00, C12M 1/22, C12M 3/00
US Classification:
4352865, 4353051, 4352841, 4352873, 4352878, 4352882, 4352931, 4353052, 4353053, 4353071, 4352883, 4352885
Abstract:
Microfluidic devices having active features such as valves, peristaltic pumps, and mixing portions are fabricated to have a thin elastomeric membrane over the active features. The active features are activated by a tactile actuator external to the membrane, for example, a commercial Braille display. The display may be computer controlled, for example by simple text editor software, to activate individual Braille protrusions or a plurality of protrusions to actuate the active portions of the microfluidic device. Integral devices can incorporate the tactile actuators in a single device, but still external to the membrane.
Process For Sorting Motile Particles From Lesser-Motile Particles And Apparatus Suitable Therefor
US Patent:
2008018, Aug 7, 2008
Filed:
Apr 2, 2008
Appl. No.:
12/061482
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Gary D. Smith - Ann Arbor MI, US
Timothy G. Schuster - Ann Arbor MI, US
Brenda S. Cho - Ann Arbor MI, US
Gary D. Smith - Ann Arbor MI, US
Timothy G. Schuster - Ann Arbor MI, US
Brenda S. Cho - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
C12N 5/06
US Classification:
435325, 435243
Abstract:
Motile particles are sorted from non-motile particles in a microfluidic sorting device wherein a stream of sort fluid containing motile and non-motile particles is caused to flow adjacent a media stream in non-turbulent fashion through a sort channel, during which flow motile particles cross the interface between the adjacent flow streams, entering the media stream, and forming a motile particle-depleted sort stream. The sorting devices are easily and inexpensively fabricated and have numerous uses, in particular sorting of motile from non-motile sperm.
Integrated Microfluidic Control Employing Programmable Tactile Actuators
US Patent:
7745211, Jun 29, 2010
Filed:
Mar 10, 2004
Appl. No.:
10/548692
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Wei Gu - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Yunseok Heo - Ann Arbor MI, US
Brenda S. Cho - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Wei Gu - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Yunseok Heo - Ann Arbor MI, US
Brenda S. Cho - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12M 1/00, C12M 1/22, C12M 3/00
US Classification:
4353051, 4352841, 4352873, 4352878, 4352882, 4352883, 4352885, 4352931, 4353052, 4353053, 4353071
Abstract:
Microfluidic devices having active features such as valves, peristaltic pumps, and mixing portions are fabricated to have a thin elastomeric membrane over the active features. The active features are activated by a tactile actuator external to the membrane, for example, a commercial Braille display. The display may be computer controlled, for example by simple text editor software, to activate individual Braille protrusions or a plurality of protrusions to actuate the active portions of the microfluidic device. Integral devices can incorporate the tactile actuators in a single device, but still external to the membrane.
Microfluidic Cell Culture Device And Method For Using Same
US Patent:
2010032, Dec 23, 2010
Filed:
Aug 11, 2010
Appl. No.:
12/854459
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Lourdes Marcella Cabrera - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Yun Seok Heo - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Lourdes Marcella Cabrera - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Yun Seok Heo - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Xiaoyue Zhu - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
C12N 5/07
US Classification:
435383
Abstract:
Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.
Microfluidic Cell Culture Device
US Patent:
2010032, Dec 23, 2010
Filed:
Aug 11, 2010
Appl. No.:
12/854465
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Lourdes Marcella Cabrera - Ann Arbor MI, US
Yun Seok Heo - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Lourdes Marcella Cabrera - Ann Arbor MI, US
Yun Seok Heo - Ann Arbor MI, US
Gary Daniel Smith - Ann Arbor MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
C12N 5/071
US Classification:
435366, 435325
Abstract:
Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.
Process For Sorting Motile Particles From Lesser-Motile Particles And Apparatus Suitable Therefor
US Patent:
2003016, Sep 4, 2003
Filed:
Feb 27, 2003
Appl. No.:
10/375373
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Gary Smith - Ann Arbor MI, US
Timothy Schuster - Ann Arbor MI, US
Brenda Cho - Ann Arbor MI, US
Gary Smith - Ann Arbor MI, US
Timothy Schuster - Ann Arbor MI, US
Brenda Cho - Ann Arbor MI, US
International Classification:
C12Q001/00
US Classification:
435/004000
Abstract:
Motile particles are sorted from non-motile particles in a microfluidic sorting device wherein a stream of sort fluid containing motile and non-motile particles is caused to flow adjacent a media stream in non-turbulent fashion through a sort channel, during which flow motile particles cross the interface between the adjacent flow streams, entering the media stream, and forming a motile particle-depleted sort stream. The sorting devices are easily and inexpensively fabricated and have numerous uses, in particular sorting of motile from non-motile sperm.
Microfluidic Cell Culture Device And Method For Using Same
US Patent:
2007008, Apr 19, 2007
Filed:
Oct 17, 2006
Appl. No.:
11/582035
Inventors:
Shuichi Takayama - Ann Arbor MI, US
Lourdes Cabrera - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Yun Heo - Ann Arbor MI, US
Gary Smith - Ann Arbor MI, US
Lourdes Cabrera - Ann Arbor MI, US
Nobuyuki Futai - Ann Arbor MI, US
Yun Heo - Ann Arbor MI, US
Gary Smith - Ann Arbor MI, US
International Classification:
H01H 29/00
US Classification:
200182000
Abstract:
Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.