Inventors:
Julia B. Gershkovich - Lexington MA, US
Peter K. Jarrett - Sudbury MA, US
Kevin C. Skinner - Andover MA, US
Gary D. Monheit - Birmingham AL, US
International Classification:
A61K 9/14, A61K 31/08, A61P 43/00
Abstract:
Methods of repairing or augmenting soft tissue in a subject are described. The methods include injecting into a subject composition comprising a biodegradable, polymerizable macromer, the macromer comprising a water soluble polymer modified with one or more biodegradable moieties; and polymerizing the macromer to provide a hydrogel, thus repairing or augmenting the soft tissue.