GARY D KRUH
Medical Practice in Philadelphia, PA
License number
Pennsylvania MD043927L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Philadelphia, PA 19111
Personal information
See more information about GARY D KRUH at radaris.comName
Address
Phone
241 S 6Th St APT 809D, Philadelphia, PA 19106
241 6Th St, Philadelphia, PA 19106
Professional information
Mpr-Related Abc Transporter Encoding Nucleic Acids And Methods Of Use Thereof
US Patent:
6803184, Oct 12, 2004
Filed:
Sep 27, 2000
Appl. No.:
09/647140
Inventors:
Gary Kruh - Philadelphia PA
Kun Lee - Cranbury NJ
Kun Lee - Cranbury NJ
Assignee:
Fox Chase Cancer Center - Philadelphia PA
International Classification:
C12Q 100
US Classification:
435 4, 4353201, 435325, 435455, 536 231, 536 235, 424 9321
Abstract:
Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded protein provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.
Mrp-Related Abc Transporter Encoding Nucleic Acids And Methods Of Use Thereof
US Patent:
7312026, Dec 25, 2007
Filed:
Jul 12, 2004
Appl. No.:
10/889503
Inventors:
Gary Kruh - Philadelphia PA, US
Kun Lee - Cranbury NJ, US
Martin Belinsky - Warminster PA, US
Lisa Bain - Townville SC, US
Kun Lee - Cranbury NJ, US
Martin Belinsky - Warminster PA, US
Lisa Bain - Townville SC, US
Assignee:
Fox Chase Cancer Center - Philadelphia PA
International Classification:
C12Q 1/00, C12N 15/00, C12N 15/63, C07H 21/04, A01N 63/00
US Classification:
435 4, 4353201, 435325, 435455, 536 231, 536 235, 424 9321
Abstract:
Novel human MOAT genes and their encoded proteins are provided herein. The MRP-related ABC transporters encoded by the disclosed nucleic acid sequences play a pivotal role in the efflux of pharmacologically beneficial reagents from tumor cells. MOAT genes and their encoded proteins provide valuable therapeutic targets for the design of anti-cancer agents which inhibit the aberrant growth of malignant cells.