Inventors:
Stella Nowicki - Galveston TX
Bogdan Nowicki - Galveston TX
Garland D. Anderson - Galveston TX
Assignee:
The Board of Regents of the University of Texas System - Austin TX
International Classification:
C12Q 168, C12P 1934, C07H 2104
Abstract:
The present invention provides a method of differentially diagnosing pelvic inflammatory disease from local infection of Neisseria gonorrhoeae in an individual, comprising the step of identifying whether the individual carries a strain of Neisseria gonorrhoeae which is stable resistant to the bacteriocidal effects of normal human serum. Also provided is a method of differentially diagnosing pelvic inflammatory disease from local infection of Neisseria gonorrhoeae in an individual, comprising the step of determining the presence of a 344 base pair DNA sequence from the 2. 2 kb sac-4 region of Neisseria gonorrhoeae in a clinical isolate obtained from said individual.