Inventors:
Peter Saggau - Houston TX, US
Olga Gliko - Houston TX, US
Gaddum Duemani Reddy - Houston TX, US
Assignee:
Baylor College of Medicine - Houston TX
International Classification:
G02F 1/33
Abstract:
The present invention is a method and apparatus that utilizes an inertia-free diffraction mechanism to control both phase and rotation of the standing wave pattern that results in super-resolution at unparalleled imaging speeds. In some embodiments of the present inventions, AODs are utilized to control period, phase, and rotation of the SW pattern in contrast to the commonly used mechano-optical principles. This allows 2D (and 3D) super-resolution imagining at high stability and speed not limited by mechanical constraints. The present invention can be utilized, for example, for real time observations of dynamic processes in living cells.