GABRIEL NUNEZ, MD
Medical Practice in Ann Arbor, MI
License number
Michigan 4301057641
Category
Medical Practice
Type
Anatomic Pathology
Address
Address
1500 Floor University Hospital Recp Pathology, Ann Arbor, MI 48109
Phone
(800) 862-7284
(734) 936-2047
(734) 936-2047
Professional information
See more information about GABRIEL NUNEZ at trustoria.com
Nod2 Nucleic Acids And Proteins
Nod2 Nucleic Acids And Proteins
US Patent:
6835815, Dec 28, 2004
Filed:
Oct 26, 2001
Appl. No.:
10/014269
Inventors:
Gabriel Nunez - Ann Arbor MI
Naohiro Inohara - Ann Arbor MI
Yasunori Ogura - Ann Arbor MI
Naohiro Inohara - Ann Arbor MI
Yasunori Ogura - Ann Arbor MI
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
C07K 1447
US Classification:
530350
Abstract:
The present invention relates to intracellular signalling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides isolated nucleotide sequence encoding Nod2, isolated Nod2 peptides, antibodies that specifically bind Nod2, methods for the detection of Nod2, and methods for screening compounds for the ability to alter Nod2 associated signal transduction.
Compositions And Methods For Identifying Apoptosis Signaling Pathway Inhibitors And Activators
Compositions And Methods For Identifying Apoptosis Signaling Pathway Inhibitors And Activators
US Patent:
6348573, Feb 19, 2002
Filed:
Apr 27, 1998
Appl. No.:
09/069023
Inventors:
Gabriel Nunez - Ann Arbor MI
Naohiro Inohara - Ann Arbor MI
Takeyoshi Koseki - Ann Arbor MI
Naohiro Inohara - Ann Arbor MI
Takeyoshi Koseki - Ann Arbor MI
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C07K 1700
US Classification:
530350, 530324, 530399, 435 71, 435 721, 435 72, 514 2
Abstract:
The invention generally relates to compositions and methods for identifying Apoptosis signaling pathway inhibitors and activators.
Methods And Compositions For Mediation Of Immune Responses And Adjuvant Activity
Methods And Compositions For Mediation Of Immune Responses And Adjuvant Activity
US Patent:
2008000, Jan 10, 2008
Filed:
Jan 10, 2007
Appl. No.:
11/651808
Inventors:
Gabriel Nunez - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61K 49/00, C12Q 1/02, C12Q 1/34, C12Q 1/68
US Classification:
424009200, 435018000, 435029000, 435006000
Abstract:
The present invention relates to methods and compositions for modulating immune responses and adjuvant activity. In particular, the present invention provides methods and compositions for screening for compounds that modulate cryopyrin signaling.
Vertebrate Apoptosis Gene: Compositions And Methods
Vertebrate Apoptosis Gene: Compositions And Methods
US Patent:
2002013, Sep 26, 2002
Filed:
Sep 12, 2001
Appl. No.:
09/952278
Inventors:
Craig Thompson - Chicago IL, US
Lawrence Boise - Chicago IL, US
Gabriel Nunez - Ann Arbor MI, US
Lawrence Boise - Chicago IL, US
Gabriel Nunez - Ann Arbor MI, US
Assignee:
The Regent of the University of Michigan
International Classification:
C12N009/99, C12N009/64, C07H021/04, C12P021/02, C12N005/06
US Classification:
435/226000, 435/325000, 435/320100, 435/069100, 536/023200, 435/184000
Abstract:
The invention relates generally to compositions of and methods for obtaining and using a polypeptide other than BCL-2 that affects programmed vertebrate cell death. The invention relates as well to polynucleotides encoding those polypeptides, recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant polypeptides. The invention further provides methods for using the isolated, recombinant polypeptides in assays designed to select and improve substances capable of altering programmed cell death for use in diagnostic, drug design and therapeutic applications.
Nod2 Nucleic Acids And Proteins
Nod2 Nucleic Acids And Proteins
US Patent:
7060493, Jun 13, 2006
Filed:
Nov 9, 2004
Appl. No.:
10/984710
Inventors:
Gabriel Nunez - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Yasunori Ogura - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Yasunori Ogura - Ann Arbor MI, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12N 5/10, C12N 1/21, C12N 1/19, C12N 15/63, C07H 21/04
US Classification:
435325, 4352523, 43525411, 4353201, 536 235
Abstract:
The present invention relates to intracellular signalling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides isolated nucleotide sequence encoding Nod2, isolated Nod2 peptides, antibodies that specifically bind Nod2, methods for the detection of Nod2, and methods for screening compounds for the ability to alter Nod2 associated signal transduction.
Modulators Of Nod2 Signaling
Modulators Of Nod2 Signaling
US Patent:
2006016, Jul 20, 2006
Filed:
Jan 12, 2006
Appl. No.:
11/331240
Inventors:
Gabriel Nunez - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Yasunori Ogura - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Yasunori Ogura - Ann Arbor MI, US
International Classification:
C12Q 1/68, G01N 33/53
US Classification:
435006000, 435007100
Abstract:
The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides methods of identifying modulators of Nod2 signaling. In particular, the present invention additionally provides methods of screening immune modulators such as adjuvants using Nod2. The present invention further provides methods of altering Nod2 signaling.
Nod2 Nucleic Acids And Proteins
Nod2 Nucleic Acids And Proteins
US Patent:
6858391, Feb 22, 2005
Filed:
Oct 26, 2001
Appl. No.:
10/002974
Inventors:
Gabriel Nunez - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Yasunori Ogura - Ann Arbor MI, US
Judy Cho - Chicago IL, US
Dan L. Nicolae - Chicago IL, US
Denise Bonen - Chicago IL, US
Naohiro Inohara - Ann Arbor MI, US
Yasunori Ogura - Ann Arbor MI, US
Judy Cho - Chicago IL, US
Dan L. Nicolae - Chicago IL, US
Denise Bonen - Chicago IL, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
C07H021/04, C12Q001/68
US Classification:
435 6, 435 911, 435 912, 536 231, 536 243
Abstract:
The present invention relates to intracellular signalling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides isolated nucleotide sequence encoding Nod2, isolated Nod2 peptides, antibodies that specifically bind Nod2, methods for the detection of Nod2, and methods for screening compounds for the ability to alter Nod2 associated signal transduction. The present invention also provides Nod2 variant alleles. The present invention further provides methods of identifying individuals at increased risk of developing Crohn's disease.
Rick3 Nucleic Acids And Proteins
Rick3 Nucleic Acids And Proteins
US Patent:
2006010, May 18, 2006
Filed:
Dec 22, 2005
Appl. No.:
11/317329
Inventors:
Gabriel Nunez - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Akihiro Muto - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Akihiro Muto - Ann Arbor MI, US
International Classification:
C12Q 1/48, C07H 21/04, C12P 21/06, C12N 9/12
US Classification:
435015000, 435194000, 435069100, 435320100, 435325000, 536023200
Abstract:
The present invention related to methods and compositions for modulating cellular signaling. In particular, the present invention relates to PKK and RICK3 proteins. The present invention further relates the to use of PKK and RICK3 proteins in modulating NF-κB signaling. The present invention thus provides novel targets for drug screening and therapeutics.
Nod Nucleic Acids And Polypeptides
Nod Nucleic Acids And Polypeptides
US Patent:
2006029, Dec 28, 2006
Filed:
Jan 26, 2006
Appl. No.:
11/340211
Inventors:
Naohiro Inohara - Ann Arbor MI, US
Gabriel Nunez - Ann Arbor MI, US
Gabriel Nunez - Ann Arbor MI, US
International Classification:
C12Q 1/68, C07H 21/04
US Classification:
435006000, 536024300
Abstract:
The present invention relates to the NOD proteins and nucleic acids encoding the NOD proteins. The present invention further provides assays for the detection of NOD polymorphisms and mutations associated with disease states, as well as methods of screening for ligands and modulators of NOD proteins.
Modulators Of Nod1 Signaling
Modulators Of Nod1 Signaling
US Patent:
2005000, Jan 13, 2005
Filed:
May 14, 2004
Appl. No.:
10/845799
Inventors:
Gabriel Nunez - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Naohiro Inohara - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12Q001/68, G01N033/53, G01N033/567, A61K038/04
US Classification:
435006000, 435007200, 514019000
Abstract:
The present invention relates to intracellular signaling molecules, in particular the Nod1 protein. The present invention provides methods of identifying modulators of Nod1 signaling. The present invention further provides methods of altering Nod1 signaling.
Medical Practice licenses in Michigan
Other Doctors licenses in Michigan
VIVIAN H LIN, Osteopathic Medicine, 24 Frank Lloyd Wright Dr Lobby C SUITE 1300, Ann Arbor, MI 48105