Inventors:
Camilla Fowst - Milan, IT
Franzanne Vreeland - Martinsville NJ
Maria Cristina Rosa Geroni - Milan, IT
Assignee:
Pharmacia Italia S.p.A. - Milan
Pharmacia Upjohn Company - Kalamazoo MI
International Classification:
A61K 3140
US Classification:
514 18, 514428, 514422, 514408, 544333, 548524, 548518, 5483147
Abstract:
The present invention relates to an administration schedule comprising the intravenous administration of a -halogen-acryloyl distamycin derivative of formula (I) wherein R is a bromine or chlorine atom; or a pharmaceutically acceptable salt thereof. The above administration allows the treatment of a variety of tumors in mammals.