Inventors:
Joseph Friedberg - Philadelphia PA, US
Franz Fogt - Gladwyne PA, US
Assignee:
The Trustees of the University of Pennsylvania - Philadelphia PA
International Classification:
G01N 21/75, C12M 1/42, B82Y 15/00
US Classification:
435 725, 4352872, 977700, 977834, 977902, 977890
Abstract:
The present invention provides compositions and methods for the detection of red blood cells antigens. The methods and compositions are based on antibodies, serving as primary antibodies or secondary antibodies, that are labeled with a rare-earth based crystal. Methods utilizing antibodies labeled with a rare-earth based crystal enhance the efficiency and accuracy of blood compatability tests and red blood cells phenotyping.