Inventors:
Martin J. Bide - Wavefield RI, US
Matthew D. Phaneuf - Ashland MA, US
William C. Quist - Brookline MA, US
Donald J. Dempsey - Newbury MA, US
Frank W. LoGerfo - Cambridge MA, US
Assignee:
University of Rhode Island - Kingston RI
Beth Israel Deaconess Medical Center - Boston MA
BioMod Surfaces - Salisbury MA
International Classification:
A61K 31/765, A61F 13/00, C08L 67/02
US Classification:
424486, 424 7806, 424 7807, 424422, 424445, 525420, 525437, 528288, 528332, 528335, 602 42, 602 48, 602 52
Abstract:
The invention features a method of treating polyester material to generate functional carboxylic acid and amine groups. These functional groups can be used as sites for covalent bond formation to attach chemical or biological moieties. This bifunctionalized polyester polymer can be used in any medical application in which biocompatible polymers are used.