FRANK PETRAGLIA, III
Medical Practice in Durham, NC
License number
Pennsylvania MT212206
Category
Medicine
Type
Graduate Medical Trainee
Address
Address
2
Durham, NC 27701
Pennsylvania
Pennsylvania
Personal information
See more information about FRANK PETRAGLIA, III at radaris.comName
Address
Phone
7616 Huron St, Philadelphia, PA 19118
608 Dorseyville Rd, Pittsburgh, PA 15238
Roanoke Rapids, NC
4509 Wingate Dr, Raleigh, NC 27609
432 Acorn Ct, Reading, PA 19605
Professional information
Cycloalkylidene Compounds As Modulators Of Estrogen Receptor
US Patent:
7799828, Sep 21, 2010
Filed:
Jun 8, 2009
Appl. No.:
12/480097
Inventors:
Jing Fang - Durham NC, US
Dennis Heyer - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Frank Navas, III - Durham NC, US
William J. Zuercher - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Dennis Heyer - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Frank Navas, III - Durham NC, US
William J. Zuercher - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Assignee:
GlaxoSmithKline LLC - Philadelphia PA
International Classification:
A61K 31/351
US Classification:
514459
Abstract:
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation.
Naphthalene Compounds As Selective Estrogen Receptor Modulators
US Patent:
7649093, Jan 19, 2010
Filed:
Jun 21, 2005
Appl. No.:
11/570838
Inventors:
Dennis Heyer - Durham NC, US
Jing Fang - Durham NC, US
Frank Navas, III - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Jennifer Poole Peckham - Durham NC, US
Philip Stewart Turnbull - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Adwoa Akwabi-Ameyaw - Durham NC, US
Jing Fang - Durham NC, US
Frank Navas, III - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Jennifer Poole Peckham - Durham NC, US
Philip Stewart Turnbull - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Adwoa Akwabi-Ameyaw - Durham NC, US
Assignee:
Glaxo Smith Kline LLC - Wilmington DE
International Classification:
C07D 471/00, C07D 295/00, A61K 31/445
US Classification:
546 86, 514319, 544386
Abstract:
The present invention relates to cycloalkylidene compounds with a variety of therapeutic uses, more particularly novel naphthalene compounds that are particularly useful for selective estrogen receptor modulation.
Cycloalkylidene Compounds As Modulators Of Estrogen Receptor
US Patent:
7569601, Aug 4, 2009
Filed:
May 14, 2007
Appl. No.:
11/748096
Inventors:
Jing Fang - Durham NC, US
Dennis Heyer - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Frank Navas, III - Durham NC, US
William J. Zuercher - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Dennis Heyer - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Frank Navas, III - Durham NC, US
William J. Zuercher - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K 31/351, C07D 315/00
US Classification:
514459, 549426
Abstract:
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation.
Imidazoline Derivatives As Alpha-1A Adrenoceptor Ligands
US Patent:
6884801, Apr 26, 2005
Filed:
Apr 28, 2000
Appl. No.:
10/019976
Inventors:
Eric Cleveland Bigham - Durham NC, US
Michael Joseph Bishop - Durham NC, US
David Harold Drewry - Durham NC, US
Deanna Trojan Garrison - Durham NC, US
Stephen Joseph Hodson - Durham NC, US
Frank Navas, III - Durham NC, US
Jason D. Speake - Durham NC, US
Michael Joseph Bishop - Durham NC, US
David Harold Drewry - Durham NC, US
Deanna Trojan Garrison - Durham NC, US
Stephen Joseph Hodson - Durham NC, US
Frank Navas, III - Durham NC, US
Jason D. Speake - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
A61K031/5375, A61K031/4164, C07D403/02, C07D413/10
US Classification:
5142358, 544106, 544139, 546184, 546210, 5483147, 5483491, 5483511, 514326, 514399
Abstract:
Compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed. Such compounds are useful in the treatment of Alpha-1A mediated diseases or conditions such as urinary incontinence.
Cycloalkylidene Compounds As Modulators Of Estrogen Receptor
US Patent:
7560589, Jul 14, 2009
Filed:
Jul 27, 2004
Appl. No.:
10/565296
Inventors:
Jonathan E. Britton - Skyland NC, US
Jing Fang - Durham NC, US
Dennis Heyer - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Frank Navas, III - Durham NC, US
William J. Zuercher - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Jing Fang - Durham NC, US
Dennis Heyer - Durham NC, US
Aaron Bayne Miller - Durham NC, US
Frank Navas, III - Durham NC, US
William J. Zuercher - Durham NC, US
Subba Reddy Katamreddy - Durham NC, US
Assignee:
SmithKline Beecham Corporation - Philadelphia PA
International Classification:
C07C 63/33
US Classification:
562491
Abstract:
The present invention relates to novel compounds with a variety of therapeutic uses, more particularly novel substituted cyclic alkylidene compounds that are particularly useful for selective estrogen receptor modulation.
Farnesoid X Receptor Agonists
US Patent:
8158665, Apr 17, 2012
Filed:
Mar 9, 2010
Appl. No.:
12/720023
Inventors:
Richard Caldwell - Durham NC, US
David Norman Deaton - Durham NC, US
Robert Blount McFadyen - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
David Norman Deaton - Durham NC, US
Robert Blount McFadyen - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
Assignee:
GlaxoSmithKline LLC - Philadelphia PA
International Classification:
A61K 31/42
US Classification:
514378
Abstract:
The present invention provides novel substituted isoxazole compounds, pharmaceutical compositions, therapeutic uses and processes for preparing the same.
Farnesoid X Receptor Agonists
US Patent:
2010012, May 13, 2010
Filed:
Oct 23, 2007
Appl. No.:
12/446594
Inventors:
David Norman Deaton - Durham NC, US
Justin Caravella - Durham NC, US
Robert Blount McFadyen - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
Justin Caravella - Durham NC, US
Robert Blount McFadyen - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
Assignee:
SMITHKLINE BEECHAM CORPORATION - Philadelphia PA
International Classification:
A61K 31/498, C07D 215/20, A61K 31/47, C07D 413/02, A61K 31/517, C07D 241/36, A61P 3/04, A61P 3/10, A61P 1/16
US Classification:
514249, 546170, 514314, 544284, 5142662, 544355
Abstract:
The present invention provides novel substituted isoxazole compounds, pharmaceutical compositions, therapeutic uses and processes for preparing the same.
Farnesoid X Receptor Agonists
US Patent:
7705028, Apr 27, 2010
Filed:
Dec 13, 2006
Appl. No.:
11/609914
Inventors:
Richard Caldwell - Durham NC, US
David Norman Deaton - Durham NC, US
Robert Blout McFayden - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
David Norman Deaton - Durham NC, US
Robert Blout McFayden - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
Assignee:
GlaxoSmithKline LLC - Philadelphia PA
International Classification:
A61K 31/42, C07D 261/06
US Classification:
514378, 548247
Abstract:
The present invention provides novel substituted isoxazole compounds, pharmaceutical compositions, therapeutic uses and processes for preparing the same.
Farnesoid X Receptor Agonists
US Patent:
2010024, Sep 30, 2010
Filed:
Jun 13, 2008
Appl. No.:
12/663722
Inventors:
David Norman Deaton - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
Frank Navas, III - Durham NC, US
Paul Kenneth Spearing - Durham NC, US
Assignee:
SMITHKLINE BEECHAM CORPORATION - Philadelphia PA
International Classification:
A61K 31/4365, C07D 497/04, A61P 1/16, C07D 413/12, A61K 31/422, C07D 413/14, A61K 31/4439, A61K 31/423
US Classification:
514301, 546114, 548247, 514378, 5462711, 514339, 548241, 514379
Abstract:
The present invention provides novel isoxazole compounds, pharmaceutical compositions, therapeutic uses and processes for preparing the same.
Pth Agonists
US Patent:
2007012, May 31, 2007
Filed:
Feb 3, 2005
Appl. No.:
10/597858
Inventors:
David Cowan - Research Triangle Park NC, US
Frank Navas III - Research Triangle Park NC, US
Jeffrey Oplinger - Research Triangle Park NC, US
Frank Navas III - Research Triangle Park NC, US
Jeffrey Oplinger - Research Triangle Park NC, US
International Classification:
A61K 31/515, C07D 239/60
US Classification:
514269000, 514270000, 544301000, 544311000
Abstract:
This invention relates to compounds of formula (I) or (II)
wherein, in either formula, independently;