Inventors:
James W. Larrick - Woodside CA
Gordon M. Ringold - Palo Alto CA
David F. Mark - Danville CA
Leo S. Lin - Walnut Creek CA
Frank M. Torti - Palo Alto CA
Assignee:
The Board of Trustees of the Cetus Corporation - Emeryvile CA
Leland Stanford Junior University - Stanford CA
International Classification:
A61K 3702, A61K 3900
Abstract:
A method for controlling weight by suppressing the normal metabolism of adipose tissue is disclosed. Administration of tumor necrosis factor (TNF) or a pharmaceutical composition containing it results in suppression of anabolism of adipose cells.