FRANCIS SPINALE, MD
Hospitals at Doughty St, Charleston, SC
License number
South Carolina 22410
Category
Hospitals
Type
Military Hospital
Address
Address
114 Doughty St RM 625, Charleston, SC 29403
Phone
(843) 876-5186
(843) 876-5187 (Fax)
(843) 876-5187 (Fax)
Personal information
See more information about FRANCIS SPINALE at radaris.comName
Address
Phone
1266 Candlewood Cir, Blythewood, SC 29016
2034 Shell Ring Cir, Mount Pleasant, SC 29466
947 Orange Grove Rd, Charleston, SC 29407
460 Piazza Ct, Mount Pleasant, SC 29464
171 Ashley Ave, Charleston, SC 29425
Organization information
See more information about FRANCIS SPINALE at bizstanding.comFrancis Spinale MD
114 Doughty St, Charleston, SC 29403
Industry:
Surgeons, Family Doctor
Phone:
(843) 876-5186 (Phone)
Francis Guy Spinale
Professional information
Predicting Atrial Fibrillation Recurrence By Protease And Protease Inhibitor Profiling
US Patent:
8506499, Aug 13, 2013
Filed:
Jan 4, 2008
Appl. No.:
12/522238
Inventors:
Rupak Mukherjee - Charleston SC, US
Michael R. Gold - Daniel Island SC, US
Francis G. Spinale - Charleston SC, US
Michael R. Gold - Daniel Island SC, US
Francis G. Spinale - Charleston SC, US
Assignee:
MUSC Foundation for Research Development - Charleston SC
International Classification:
A61B 5/02
US Classification:
600508
Abstract:
Disclosed herein are methods of and systems for predicting recurrence of atrial fibrillation comprising protease and protease inhibitor profiling. The levels of matrix metalloproteinases (MMPs) and/or tissue inhibitor metalloproteinases (TIMPs) are analyzed to predict the recurrence of atrial fibrillation, and further to predict whether cardioversion will provide a successful therapy.
System And Method For Filtering Leukocytes In Cardiac Surgery
US Patent:
2005021, Sep 29, 2005
Filed:
Mar 3, 2005
Appl. No.:
11/071874
Inventors:
Francis Spinale - Charleston SC, US
Joseph Sistino - Charleston SC, US
Jessica Garner - Milford OH, US
John Ikonomidis - Mt. Pleasant SC, US
Robert Stroud - Mt. Pleasant SC, US
Joseph Sistino - Charleston SC, US
Jessica Garner - Milford OH, US
John Ikonomidis - Mt. Pleasant SC, US
Robert Stroud - Mt. Pleasant SC, US
International Classification:
A61M037/00
US Classification:
604006030, 210323100
Abstract:
According to one embodiment, a leukocyte reducing filter system comprises a delivery line comprising a plurality of branches, at least a plurality of said branches further comprising a leukocyte reducing filter interposed into said branch, and a stopping mechanism for selectively stopping fluid flow through each of said branches.
Dr. Francis G Spinale, Columbia SC - MD (Doctor of Medicine)
Specialties:
General Surgery
Address:
6439 Garners Ferry Rd SUITE 28, Columbia 29209
(803) 777-3964 (Phone), (843) 876-5186 (Fax)
631 Sumter St SUITE 4, Columbia 29208
CARDIOVASCULAR THERAPY SURGERY RESEARCH
114 Doughty St SUITE 625, Charleston 29425
(843) 876-5186 (Phone), (843) 876-5187 (Fax)
(803) 777-3964 (Phone), (843) 876-5186 (Fax)
631 Sumter St SUITE 4, Columbia 29208
CARDIOVASCULAR THERAPY SURGERY RESEARCH
114 Doughty St SUITE 625, Charleston 29425
(843) 876-5186 (Phone), (843) 876-5187 (Fax)
Languages:
English
Education:
Medical School
Medical University of South Carolina
Graduated: 1995
Medical University of South Carolina
Graduated: 1995
Assessing Left Ventricular Remodeling Via Temporal Detection And Measurement Of Microrna In Body Fluids
US Patent:
8592151, Nov 26, 2013
Filed:
Nov 11, 2010
Appl. No.:
12/944670
Inventors:
Francis G. Spinale - Charleston SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Assignee:
MUSC Foundation for Research Development - Charleston SC
International Classification:
C12Q 1/68
US Classification:
435 61, 435 611
Abstract:
Disclosed are methods and materials for assessing cardiac failure, cardiac hypertrophy, and left ventricular remodeling using microRNA levels. The level of microRNAs can be measured in a body fluid, such as plasma and serum.
Method For Reducing Pericardial Fibrosis And Adhesion Formation
US Patent:
6211217, Apr 3, 2001
Filed:
Mar 16, 1999
Appl. No.:
9/270412
Inventors:
Francis G. Spinale - Charleston SC
Marc de Gasparo - Rossemaison, CH
Marc de Gasparo - Rossemaison, CH
Assignee:
Novartis AG - Basel
International Classification:
A61K 3141
US Classification:
514381
Abstract:
Disclosed are methods of reducing fibrosis and adhesion formation in a surgical patient wherein the AT. sub. 1 receptor antagonist, the compound (S)-N-(1-carboxy-2-methylprop-1-yl)-N-pentanoyl-N-[2'(1H-tetrazol-5-yl)bip henyl-4-yl-methyl]amine (valsartan) of formula ##STR1##
or a salt thereof, in particular a pharmaceutically acceptable salt thereof, is administered to the patient. In particular, disclosed are methods of reducing pericardial fibrosis and pericardial adhesion formation which results from cardiac surgery.
Method Of Treating Or Preventing Cardiac Arrhythmia Employing An N-Substituted Heterocyclic Derivative
US Patent:
5541209, Jul 30, 1996
Filed:
Aug 22, 1994
Appl. No.:
8/293985
Inventors:
Francis G. Spinale - Charleston SC
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 3141
US Classification:
514381
Abstract:
The invention relates to the use of an N-substituted heterocyclic derivative and its pharmaceutically acceptable salts for the treatment or prevention of cardiac arrhythmia. These derivatives have the structure ##STR1##.
Detecting Diastolic Heart Failure By Protease And Protease Inhibitor Plasma Profiling
US Patent:
2009022, Sep 3, 2009
Filed:
Apr 24, 2007
Appl. No.:
12/299999
Inventors:
Francis G. Spinale - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
Robert E. Stroud - Mt. Pleasant SC, US
Michael R. Zile - Charleston SC, US
International Classification:
C12Q 1/37
US Classification:
435 23
Abstract:
Disclosed herein are methods of detecting and predicting diastolic heart failure and predicting congestive heart failure comprise protease and protease inhibitor profiling.
Methods Of Modifying Myocardial Infarction Expansion
US Patent:
2009002, Jan 22, 2009
Filed:
Jan 17, 2008
Appl. No.:
12/016180
Inventors:
Eugene T. Michal - San Francisco CA, US
Shubhayu Basu - Mountain View CA, US
Alexander J. Sheehy - Menlo Park CA, US
Francis G. Spinale - Charleston SC, US
Rupak Mukherjee - Charleston SC, US
Shubhayu Basu - Mountain View CA, US
Alexander J. Sheehy - Menlo Park CA, US
Francis G. Spinale - Charleston SC, US
Rupak Mukherjee - Charleston SC, US
International Classification:
A61K 33/14, C12N 5/06, A61P 9/00
US Classification:
424682, 435 11
Abstract:
A bioscaffolding can be formed within a post-myocardial infarct region sufficient to cause attenuation of a rate of myocardial infarct expansion. A bioscaffolding may further be formed in the post-myocardial infarct region to cause an increase in posterior left ventricular wall thickness. The gel or bioscaffolding can be formed from a mixture of gel components of different gelation systems. For example, a bioscaffolding can be formed by mixing at least two different components of at least two different two-component gelation systems to form a first mixture and by mixing at least two different components (other than the components that make up the first mixture) of the at least two different two-component gelation systems to form a second mixture.
Systems And Methods For In Vivo Measurement Of Interstitial Biological Activity, Processes And/Or Compositions
US Patent:
2010001, Jan 21, 2010
Filed:
Oct 31, 2007
Appl. No.:
12/513116
Inventors:
Francis G. Spinale - Charleston SC, US
Robert Stroud - Mount Pleasant SC, US
Michael Looper - Mount Pleasant SC, US
Anne Deschamps - Mount Plesant SC, US
Robert Stroud - Mount Pleasant SC, US
Michael Looper - Mount Pleasant SC, US
Anne Deschamps - Mount Plesant SC, US
Assignee:
MUSC Foundation for Research Developement - Charleston SC
International Classification:
A61B 5/1459
US Classification:
600342
Abstract:
Provided are systems and methods for detecting and/or measuring in vivo interstitial biological activity, processes, and or compounds in human or animal subjects.
Methods Of Treating Pulmonary Disease
US Patent:
2004025, Dec 23, 2004
Filed:
Aug 17, 2004
Appl. No.:
10/488573
Inventors:
Glenn Smits - Oxford MA, US
Francis Spinale - Charleston SC, US
Francis Spinale - Charleston SC, US
International Classification:
A61K031/522
US Classification:
514/263330, 514/263340
Abstract:
Methods useful for reducing pulmonary vasoconstriction or improving pulmonary hemodynamics in a patient are disclosed. More particularly, this invention relates to administering Aadenosine receptor antagonists to reduce pulmonary vasoconstriction and improve pulmonary hemodynamics.