FRANCIS MARCHLINSKI
Medical Practice in Cynwyd, PA

License number
Pennsylvania MD021144E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Cynwyd, PA 19004
LicenseFiles verified this license of Apr 25, 2017 at the Pennsylvania Licensing System.

Professional information

Francis Marchlinski Photo 1

Method Of Using Endocardial Impedance For Determining Electrode-Tissue Contact, Appropriate Sites For Arrhythmia Ablation And Tissue Heating During Ablation

US Patent:
5447529, Sep 5, 1995
Filed:
Jan 28, 1994
Appl. No.:
8/188514
Inventors:
Francis E. Marchlinski - Bala Cynwyd PA
David S. Schwartzman - Philadelphia PA
Mark S. Mirotznik - Silver Spring MD
Kenneth R. Foster - Haverford PA
Charles D. Gottleb - Wynnewood PA
Isaac Chang - Philadelphia PA
Assignee:
Philadelphia Heart Institute - Philadelphia PA
The Trustees of the University of Pennsylvania - Philadelphia PA
Catholic University of America - Washington DC
International Classification:
A61B 1739, A61N 105
US Classification:
607 99
Abstract:
A method of locating infarcted myocardial tissue in a beating heart includes the step of inserting an impedance measuring tip of a catheter into the chamber of the beating heart, particularly the left or right ventricle, and measuring the impedance of the endocardium at various locations within the chamber of the beating heart. The values measured are compared to impedance values with a predetermined range of values to identify an infarcted area of myocardium and distinguish such area from normal myocardium. The measurements are also compared to a range of values for an infarction border zone. In accordance with the invention, the infarction border zone may be located. The infarction border zone is a significant source of arrhythmia, and particularly of ventricular tachycardia. Further, in accordance with the methods of the present invention, the risk of arrhythmia in a beating heart may be substantially reduced or eliminated by ablating endocardium within the infarction border zone utilizing the same catheter tip. Impedance measurements may also be utilized to assess the adequacy of the electrode-tissue contact, particularly in a fluid filled body organ or cavity.

Francis Marchlinski Photo 2

Method Of Using Endocardial Impedance For Determining Electrode-Tissue Contact

US Patent:
5673704, Oct 7, 1997
Filed:
May 28, 1996
Appl. No.:
8/654197
Inventors:
Francis E. Marchlinski - Bala Cynwyd PA
David S. Schwartzman - Philadelphia PA
Mark S. Mirotznik - Silver Spring MD
Kenneth R. Foster - Haverford PA
Charles D. Gottlieb - Wynnewood PA
Isaac Chang - Philadelphia PA
International Classification:
A61B 1739, A61N 105
US Classification:
128739
Abstract:
A method of locating infarcted myocardial tissue in a beating heart includes the step of inserting an impedance measuring tip of a catheter into the chamber of the beating heart, particularly the left or right ventricle, and measuring the impedance of the endocardium at various locations within the chamber of the beating heart. The values measured are compared to impedance values with a predetermined range of values to identify an infarcted area of myocardium and distinguish such area from normal myocardium. The measurements are also compared to a range of values for an infarction border zone. In accordance with the invention, the infarction border zone may be located. The infarction border zone is a significant source of arrhythmia, and particularly of ventricular tachycardia. Further, in accordance with the methods of the present invention, the risk of arrhythmia in a beating heart may be substantially reduced or eliminated by ablating endocardium within the infarction border zone utilizing the same catheter tip. Impedance measurements may also be utilized to assess the adequacy of the electrode-tissue contact, particularly in a fluid filled body organ or cavity.

Francis Marchlinski Photo 3

Method Of Using Endocardial Impedance For Assessing Tissue Heating During Ablation

US Patent:
5562721, Oct 8, 1996
Filed:
May 10, 1995
Appl. No.:
8/438326
Inventors:
Francis E. Marchlinski - Bala Cynwyd PA
David S Schwartzman - Philadelphia PA
Mark S. Mirotznik - Silver Spring MD
Kenneth R. Foster - Haverford PA
Charles D. Gottlieb - Wynnewood PA
Isaac Chang - Philadelphia PA
Assignee:
University of Pennsylvania - Philadelphia PA
Philadelphia Heart Institute - Philadelphia PA
Catholic University of America - Washington DC
International Classification:
A61B 1739, A61N 105
US Classification:
607 99
Abstract:
A method of locating infarcted myocardial tissue in a beating heart includes the step of inserting an impedance measuring tip of a catheter into the chamber of the beating heart, particularly the left or right ventricle, and measuring the impedance of the endocardium at various locations within the chamber of the beating heart. The values measured are compared to impedance values with a predetermined range of values to identify an infarcted area of myocardium and distinguish such area from normal myocardium. The measurements are also compared to a range of values for an infarction border zone. In accordance with the invention, the infarction border zone may be located. The infarction border zone is a significant source of arrhythmia, and particularly of ventricular tachycardia. Further, in accordance with the methods of the present invention, the risk of arrhythmia in a beating heart may be substantially reduced or eliminated by ablating endocardium within the infarction border zone utilizing the same catheter tip. Impedance measurements may also be utilized to assess the adequacy of the electrode-tissue contact, particularly in a fluid filled body organ or cavity.

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